Angiotensin I-converting enzyme (ACE) inactivator, with the CAS number 144085-32-5, refers to a class of compounds that inhibit the activity of the angiotensin-converting enzyme. This enzyme plays a crucial role in the renin-angiotensin system, which regulates blood pressure and fluid balance. By inhibiting ACE, these substances help to decrease the production of angiotensin II, a potent vasoconstrictor, thereby leading to vasodilation and reduced blood pressure. Characteristics of ACE inhibitors include their ability to improve cardiovascular health, manage hypertension, and provide renal protection in certain conditions. They are often used in the treatment of heart failure, hypertension, and chronic kidney disease. The pharmacological effects of ACE inhibitors can vary based on their chemical structure, but they generally exhibit good oral bioavailability and a favorable safety profile. Common side effects may include cough, elevated potassium levels, and, in rare cases, angioedema. Overall, ACE inactivators are significant in clinical medicine for their role in managing cardiovascular diseases.

angiotensin I-converting enzyme*inactivator

144085-32-5: Angiotensin I-converting enzyme (ACE) inactivator, with the CAS number 144085-32-5, refers to a class of compounds that inhibit the activity of the angiotensin-converting enzyme. This enzyme plays a crucial role in the renin-angiotensin system, which regulates blood pressure and fluid balance. By inhibiting ACE, these substances help to decrease the production of angiotensin II, a potent vasoconstrictor, thereby leading to vasodilation and reduced blood pressure. Characteristics of ACE inhibitors include their ability to improve cardiovascular health, manage hypertension, and provide renal protection in certain conditions. They are often used in the treatment of heart failure, hypertension, and chronic kidney disease. The pharmacological effects of ACE inhibitors can vary based on their chemical structure, but they generally exhibit good oral bioavailability and a favorable safety profile. Common side effects may include cough, elevated potassium levels, and, in rare cases, angioedema. Overall, ACE inactivators are significant in clinical medicine for their role in managing cardiovascular diseases.

<p>Cyanoac-Phe-Phe-OH is a hydrolytic enzyme that irreversibly inactivates the ACE enzyme. It acts as an inhibitor of angiotensin-converting enzyme and inhibits the conversion of angiotensin I to angiotensin II, which is involved in blood pressure regulation. Cyanoac-Phe-Phe-OH has been shown to be more potent than captopril, another ACE inhibitor. It also has a longer half life and greater selectivity for ACE over other serine proteases.</p>

CAS 144085-32-5

angiotensin I-converting enzyme*inactivator

Angiotensin I-Converting Enzyme (ACE) Inactivator Cyanoac-Phe-Phe-OH

Ref: 3D-FA111039