CAS 144089-96-3

5′-O-[Bis(4-methoxyphenyl)phenylmethyl]-2′-deoxy-2′-fluoro-N-(2-methyl-1-oxopropyl)guanosine

Description:

5′-O-[Bis(4-methoxyphenyl)phenylmethyl]-2′-deoxy-2′-fluoro-N-(2-methyl-1-oxopropyl)guanosine, with the CAS number 144089-96-3, is a synthetic nucleoside analog that exhibits unique structural characteristics due to the presence of a modified guanosine backbone. This compound features a 2′-deoxy-2′-fluoro modification, which enhances its stability and resistance to enzymatic degradation, making it of interest in medicinal chemistry and pharmaceutical applications. The bis(4-methoxyphenyl)phenylmethyl group contributes to its lipophilicity, potentially influencing its bioavailability and interaction with biological targets. The presence of the N-(2-methyl-1-oxopropyl) substituent may also affect its pharmacological properties, including binding affinity and selectivity towards nucleic acid targets. Overall, this compound's unique modifications position it as a candidate for further research in antiviral or anticancer therapies, where nucleoside analogs play a crucial role in inhibiting viral replication or tumor growth. Its detailed characterization would typically involve spectroscopic methods and biological assays to elucidate its mechanism of action and therapeutic potential.

Formula: C₃₅H₃₆FN₅O₇

InChI: InChI=1S/C35H36FN5O7/c1-20(2)31(43)39-34-38-30-28(32(44)40-34)37-19-41(30)33-27(36)29(42)26(48-33)18-47-35(21-8-6-5-7-9-21,22-10-14-24(45-3)15-11-22)23-12-16-25(46-4)17-13-23/h5-17,19-20,26-27,29,33,42H,18H2,1-4H3,(H2,38,39,40,43,44)/t26-,27-,29-,33-/m1/s1

InChI key: InChIKey=QQQXVSXVBFQISZ-UNVYQVKTSA-N

SMILES: C(OC[C@H]1O[C@H]([C@H](F)[C@@H]1O)N2C3=C(N=C2)C(=O)N=C(NC(C(C)C)=O)N3)(C4=CC=C(OC)C=C4)(C5=CC=C(OC)C=C5)C6=CC=CC=C6

Synonyms:

• Guanosine, 5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-deoxy-2′-fluoro-N-(2-methyl-1-oxopropyl)-
• 5′-O-[Bis(4-methoxyphenyl)phenylmethyl]-2′-deoxy-2′-fluoro-N-(2-methyl-1-oxopropyl)guanosine

5'-O-Dmt-n2-isobutyryl-2'-fluoro-2'-deoxyguanosine

CAS: 144089-96-3

Formula: C₃₅H₃₆FN₅O₇

Purity: 98%

Color and Shape: Solid

Molecular weight: 657.6880

Ref: IN-DA001IWL

DMT-2'-F-iBu-G

CAS: 144089-96-3

DMT-2'-F-iBu-G

Purity: 97%

Molecular weight: 657.69g/mol

Ref: 54-PC110272

2'-Deoxy-5'-O-DMT-2'-fluoro-N2-isobutyrylguanosine

CAS: 144089-96-3

2'-Deoxy-5'-O-DMT-2'-fluoro-N2-isobutyrylguanosine is a synthetic nucleoside. It is an activator for DNA synthesis and has anticancer, antiviral and antifungal properties. This product can be used as a reagent in the synthesis of DNA or RNA. This compound also has high purity and high quality.

Formula: C₃₅H₃₆FN₅O₇

Purity: Min. 95%

Color and Shape: Off-White Powder

Molecular weight: 657.7 g/mol

Ref: 3D-ND08524

N-{9-[(2R,3R,4R,5R)-5-{[bis(4-methoxyphenyl)(phenyl)methoxy]methyl}-3-fluoro-4-hydroxyoxolan-2-yl]-6-oxo-6,9-dihydro-1H-purin-2-yl}-2-methylpropanamide

CAS: 144089-96-3

Purity: 97%

Molecular weight: 657.699

Ref: 10-F985960

N-(9-((2R,3R,4R,5R)-5-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3-fluoro-4-hydroxytetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-3H-purin-2-yl)isobutyramide

CAS: 144089-96-3

Purity: 98%

Molecular weight: 657.6989746

Ref: 10-F691377