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CAS 144119-12-0

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(R)-Alpha,Alpha-Diphenylmethylprolinol

Description:
(R)-Alpha,Alpha-Diphenylmethylprolinol, with the CAS number 144119-12-0, is a chiral organic compound that belongs to the class of prolinol derivatives. It features a proline backbone substituted with two phenyl groups at the alpha position, contributing to its unique stereochemistry and potential applications in asymmetric synthesis. This compound is characterized by its ability to act as a chiral auxiliary or catalyst in various organic reactions, particularly in enantioselective transformations. Its structural features include a tertiary amine and hydroxyl functional groups, which can participate in hydrogen bonding, influencing its solubility and reactivity. The presence of the diphenylmethyl group enhances its steric properties, making it useful in the development of pharmaceuticals and fine chemicals. Additionally, (R)-Alpha,Alpha-Diphenylmethylprolinol is of interest in the field of medicinal chemistry due to its potential biological activity and role in the synthesis of biologically relevant molecules. Overall, its unique structural characteristics make it a valuable compound in synthetic organic chemistry.
Formula:C18H22NO
InChI:InChI=1/C18H21NO/c1-19-14-8-13-17(19)18(20,15-9-4-2-5-10-15)16-11-6-3-7-12-16/h2-7,9-12,17,20H,8,13-14H2,1H3/p+1/t17-/m1/s1
Synonyms:
  • alpha,alpha-Diphenyl-N-methyl-D-prolinol
  • (R)-alpha,alpha-Diphenyl-N-methyl-2-pyrrolidinemethanol
  • (R)-N-Methyl-alpha,alpha-diphenylpyrrolidinemethanol
  • (R)-(-)-2-[Hydroxy(diphenyl)methyl]-1-methylpyrrolidine
  • α,α-Diphenyl-N-methyl-D-prolinol
  • [(2R)-1-methylpyrrolidin-2-yl](diphenyl)methanol
  • (2R)-2-[hydroxy(diphenyl)methyl]-1-methylpyrrolidinium
  • 1,1,1-Diphenyl-(n-methyl-pyrroline-2yl)-methanol
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