CAS 144143-96-4

2-Thiophenepropanoic acid, α-[[2-butyl-1-[(4-carboxyphenyl)methyl]-1H-imidazol-5-yl]methylene]-, (αE)-, methanesulfonate (1:1)

Description:

2-Thiophenepropanoic acid, α-[[2-butyl-1-[(4-carboxyphenyl)methyl]-1H-imidazol-5-yl]methylene]-, (αE)-, methanesulfonate (1:1) is a complex organic compound characterized by its unique structural features, including a thiophene ring and an imidazole moiety. This compound exhibits both acidic and basic properties due to the presence of carboxylic acid and imidazole functionalities, which can participate in various chemical reactions, including proton transfer and coordination with metal ions. The methanesulfonate group enhances its solubility in polar solvents, making it suitable for various applications in organic synthesis and medicinal chemistry. Additionally, the presence of the butyl and phenyl groups contributes to its hydrophobic characteristics, influencing its biological activity and interaction with cellular targets. The compound's stereochemistry, indicated by the (αE) designation, suggests specific spatial arrangements that may affect its reactivity and binding properties. Overall, this substance is of interest in pharmaceutical research, particularly for its potential therapeutic applications.

Formula: C₂₃H₂₄N₂O₄S·CH₄O₃S

InChI: InChI=1S/C23H24N2O4S.CH4O3S/c1-2-3-6-21-24-14-19(12-18(23(28)29)13-20-5-4-11-30-20)25(21)15-16-7-9-17(10-8-16)22(26)27;1-5(2,3)4/h4-5,7-12,14H,2-3,6,13,15H2,1H3,(H,26,27)(H,28,29);1H3,(H,2,3,4)/b18-12+;

InChI key: InChIKey=DJSLTDBPKHORNY-XMMWENQYSA-N

SMILES: C(N1C(/C=C(\CC2=CC=CS2)/C(O)=O)=CN=C1CCCC)C3=CC=C(C(O)=O)C=C3.S(C)(=O)(=O)O

Synonyms:

• 2-Thiophenepropanoic acid, α-[[2-butyl-1-[(4-carboxyphenyl)methyl]-1H-imidazol-5-yl]methylene]-, (E)-, monomethanesulfonate
• 2-Thiophenepropanoic acid, α-[[2-butyl-1-[(4-carboxyphenyl)methyl]-1H-imidazol-5-yl]methylene]-, (αE)-, methanesulfonate (1:1)
• 2-Thiophenepropanoic acid, α-[[2-butyl-1-[(4-carboxyphenyl)methyl]-1H-imidazol-5-yl]methylene]-, (αE)-, monomethanesulfonate
• 4-({2-butyl-5-[(1E)-2-carboxy-3-thiophen-2-ylprop-1-en-1-yl]-1H-imidazol-1-yl}methyl)benzoic acid methanesulfonate
• 4-[[2-Butyl-5-(2-Carboxy-3-Thiophen-2-Yl-Prop-1-Enyl)-Imidazol-1-Yl]Methyl]Benzoic Acid Mesylate
• Eprosartan Methanesulfonate
• Skf 108566J
• Eprosartan mesylate

Eprosartan Mesylate

CAS: 133040-01-4, 144143-96-4

Formula: C₂₃H₂₄N₂O₄S·CH₄O₃S

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 520.62

Ref: 3B-E1161

Eprosartan Mesylate ((E)-2-Butyl-1-(p-carboxybenzyl)-α-2-thenylimidazole-5-acrylic acid, monomethanesulfonate)

CAS: 144143-96-4

Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoi

Formula: C₂₃H₂₄N₂O₄S·CH₄O₃S

Color and Shape: White Crystalline Powder

Molecular weight: 424.14568

Ref: 45-1238217

4-({2-butyl-5-[(1E)-2-carboxy-2-(thiophen-2-ylmethyl)eth-1-en-1-yl]-1H-imidazol-1-yl}methyl)benzoic acid; methanesulfonic acid

CAS: 144143-96-4

Formula: C₂₄H₂₈N₂O₇S₂

Purity: 99%

Color and Shape: Solid

Molecular weight: 520.6183

Ref: IN-DA001IZZ

Eprosartan Mesylate

CAS: 144143-96-4

Eprosartan Mesylate

Purity: 99%

Molecular weight: 520.62g/mol

Ref: 54-OR1028758

Eprosartan Mesylate

CAS: 144143-96-4

Formula: C₂₃H₂₄N₂O₄S·CH₄O₃S

Color and Shape: White To Off-White Solid

Molecular weight: 424.52 96.11

Ref: 4Z-E-151

Eprosartan Mesylate

CAS: 144143-96-4

Eprosartan Mesylate

Purity: ≥98%

Molecular weight: 520.62g/mol

Ref: 54-BUP15659

Eprosartan mesylate

CAS: 144143-96-4

Formula: C₂₃H₂₄N₂O₄S·CH₄O₃S

Molecular weight: 520.62

Ref: 7W-GP8368

Eprosartan mesylate

Controlled Product

CAS: 144143-96-4

Formula: C₂₃H₂₄N₂O₄S·CH₄O₃S

Color and Shape: Neat

Molecular weight: 520.62

Ref: 04-C13188000

Eprosartan Mesilate

Controlled Product

CAS: 144143-96-4

Formula: C₂₃H₂₄N₂O₄S·CH₄O₃S

Color and Shape: Neat

Molecular weight: 520.62

Ref: 86-MM1577.00

Eprosartan Mesylate

CAS: 144143-96-4

Eprosartan Mesylate (SKF-108566J) is a competitive and reversible Angiotensin II Receptor Blocker.

Formula: C₂₃H₂₄N₂O₄S·CH₄O₃S

Purity: 99.72% - 99.93%

Color and Shape: A White To Off- White Powder

Molecular weight: 520.62

Ref: TM-T2531

Eprosartan Mesylate

Controlled Product

CAS: 144143-96-4

Applications Eprosartan Mesylate is an angiotensin II receptor antagonists. Eprosartan Mesylate is used as an antihypertensive agent.
References Sheng, J. et al.: J. Pharmac. Sci., 88., 1021 (1999); Punzi, H.A. et al.: J. Hum. Hypertens., 18, 655 (2004);

Formula: C₂₃H₂₄N₂O₄S·CH₄O₃S

Color and Shape: Neat

Molecular weight: 520.62

Ref: TR-E590105

Eprosartan Mesylate

CAS: 144143-96-4

Formula: C₂₃H₂₄N₂O₄SCH₄O₃S

Molecular weight: 424.52 : 96.1

Ref: ST-EA-CP-E64008

Eprosartan mesylate

CAS: 144143-96-4

Eprosartan mesylate is an angiotensin II receptor antagonist and a prodrug of eprosartan. It is used in the treatment of hypertension, congestive heart failure, and for the prophylaxis of organ rejection in renal transplantation. This drug has been shown to inhibit the activation of nuclear factor-κB (NF-κB) and the production of inflammatory cytokines such as growth factor-β1 (GF-β1). Eprosartan mesylate has also been shown to have a beneficial effect on experimental models of type 2 diabetes and metabolic disorders. In clinical trials, it was found that losartan had similar effects on lowering blood pressure as eprosartan mesylate, but the combination increased blood pressure more than either agent alone. Eprosartan mesylate should not be taken with drugs that are metabolized by cytochrome P450 enzymes because they may lead to serious adverse effects such

Formula: C₂₃H₂₄N₂O₄S•CH₄O₃S

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 520.62 g/mol

Ref: 3D-FE61516