CAS 144164-11-4: 1,3-Thiazol-5-ylmethyl N-[(1S,2S,4S)-4-amino-1-benzyl-2-hydroxy-5-phenylpentyl]carbamate

Description: 1,3-Thiazol-5-ylmethyl N-[(1S,2S,4S)-4-amino-1-benzyl-2-hydroxy-5-phenylpentyl]carbamate, with CAS number 144164-11-4, is a chemical compound characterized by its complex structure that includes a thiazole ring and a carbamate functional group. The thiazole moiety contributes to its potential biological activity, often associated with antimicrobial and antifungal properties. The presence of the amino and hydroxy groups in the pentyl chain suggests that the compound may exhibit hydrogen bonding capabilities, influencing its solubility and reactivity. Additionally, the benzyl and phenyl groups can enhance lipophilicity, potentially affecting its pharmacokinetic properties. This compound may be of interest in medicinal chemistry, particularly in the development of therapeutic agents, due to its unique structural features that could interact with biological targets. However, specific characteristics such as melting point, solubility, and stability would require empirical data for comprehensive understanding and application in research or industry.

Formula: C₂₃H₂₇N₃O₃S

InChI: InChI=1S/C23H27N3O3S/c24-19(11-17-7-3-1-4-8-17)13-22(27)21(12-18-9-5-2-6-10-18)26-23(28)29-15-20-14-25-16-30-20/h1-10,14,16,19,21-22,27H,11-13,15,24H2,(H,26,28)/t19-,21-,22-/m0/s1

InChI key: InChIKey=HBPTXDXGWDVDON-BVSLBCMMSA-N

SMILES: O=C(OCC=1SC=NC1)NC(CC=2C=CC=CC2)C(O)CC(N)CC=3C=CC=CC3

Synonyms:

• 1,3-Thiazol-5-ylmethyl N-[(1S,2S,4S)-4-amino-1-benzyl-2-hydroxy-5-phenylpentyl]carbamate
• 1,3-thiazol-5-ylmethyl [(1S,2S,4S)-4-amino-1-benzyl-2-hydroxy-5-phenylpentyl]carbamate
• 2S,3S,5S-5-Amino-2-[N-[[(5-Thiazolyl)Methoxy]Carbonyl]Amino]-1,6-Diphenyl-3-Hydroxyhexane
• Carbamic acid, N-[(1S,2S,4S)-4-amino-2-hydroxy-5-phenyl-1-(phenylmethyl)pentyl]-, 5-thiazolylmethyl ester
• Carbamic acid, [(1S,2S,4S)-4-amino-2-hydroxy-5-phenyl-1-(phenylmethyl)pentyl]-, 5-thiazolylmethyl ester
• Carbamic acid, [4-amino-2-hydroxy-5-phenyl-1-(phenylmethyl)pentyl]-, 5-thiazolylmethyl ester, [1S-(1R*,2R*,4R*)]-
• Rt-10
• thiazol-5-ylmethyl (2S,3S,5S)-5-amino-3-hydroxy-1,6-diphenylhexan-2-ylcarbamate
• (2S,3S,5S)-5-amino-2-(N-((5-thiazolyl)methoxycarbonyl)amino)-1,6-diphenyl-3-hydroxyhexane

Carbamic acid, N-[(1S,2S,4S)-4-amino-2-hydroxy-5-phenyl-1-(phenylmethyl)pentyl]-, 5-thiazolylmethyl ester

CAS: 144164-11-4

• Formula: C₂₃H₂₇N₃O₃S
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 425.5438

(2S,3S,5S)-5-Amino-2-(N-((5-Thiazolyl)-Methoxycarbonyl)Amino)-3-Hydroxy-1,6-Diphenylhexane

CAS: 144164-11-4

• Purity: 98%
• Molecular weight: 425.55g/mol

Thiazol-5-ylmethyl [(1S,2S,4S)-4-Amino-1-benzyl-2-hydroxy-5-phenylpentyl]carbamate

CAS: 144164-11-4

• Formula: C₂₃H₂₇N₃O₃S
• Color and Shape: Neat
• Molecular weight: 425.54

Ritonavir Impurity 20

CAS: 144164-11-4

• Formula: C₂₃H₂₇N₃O₃S
• Molecular weight: 425.55

Thiazol-5-ylmethyl ((2S,3S,5S)-5-amino-3-hydroxy-1,6-diphenylhexan-2-yl)carbamate

CAS: 144164-11-4

• Purity: 95%
• Molecular weight: 425.54998779296875

2S,3S,5S-5-Amino-2-[N-[[(5-thiozolyl)methoxy]carbonyl]amino]-1,6-diphenyl-3-hydroxyhexane

CAS: 144164-11-4

• Formula: C₂₃H₂₇N₃O₃S
• Color and Shape: Neat
• Molecular weight: 425.54

2S,3S,5S-5-Amino-2-[N-[[(5-thiozolyl)methoxy]carbonyl]amino]-1,6-diphenyl-3-hydroxyhexane

CAS: 144164-11-4

2S,3S,5S-5-Amino-2-[N-[[(5-thiozolyl)methoxy]carbonyl]amino]-1,6-diphenyl-3-hydroxyhexane is a pharmaceutical intermediate that is used in the synthesis of ritonavir. It can …

• Formula: C₂₃H₂₇N₃O₃S
• Purity: Min. 95%
• Molecular weight: 425.54 g/mol