CAS 1441674-54-9

ledipasvir compd.with acetone

Description:

Ledipasvir, a key component in the treatment of hepatitis C, is often formulated as a compound with acetone, which serves as a solvent in various applications. The chemical structure of ledipasvir features a complex arrangement of functional groups that contribute to its antiviral activity, specifically targeting the NS5A protein of the hepatitis C virus. This compound is characterized by its high potency and selectivity, making it effective in inhibiting viral replication. The presence of acetone in the formulation can influence the solubility and stability of ledipasvir, facilitating its use in pharmaceutical preparations. In terms of physical properties, ledipasvir is typically a solid at room temperature, and its interactions with acetone can affect its crystallization and bioavailability. Safety data sheets indicate that while ledipasvir itself has a favorable safety profile, appropriate handling and storage conditions should be observed due to the presence of acetone, which is flammable and may pose health risks if inhaled or ingested. Overall, the combination of ledipasvir with acetone is significant in enhancing the efficacy of hepatitis C treatments.

Synonyms:

• Ledipasvir Acetone

Carbamic acid, N-[(1S)-1-[[(6S)-6-[5-[9,9-difluoro-7-[2-[(1R,3S,4S)-2-[(2S)-2-[(methoxycarbonyl)amino]-3-methyl-1-oxobutyl]-2-azabicyclo[2.2.1]hept-3-yl]-1H-benzimidazol-6-yl]-9H-fluoren-2-yl]-1H-imidazol-2-yl]-5-azaspiro[2.4]hept-5-yl]carbonyl]-2-methylpropyl]-, methyl ester, compd. with 2-propanone (1:1)

CAS: 1441674-54-9

Formula: C₅₂H₆₀F₂N₈O₇

Purity: 98%

Color and Shape: Solid

Molecular weight: 947.0790

Ref: IN-DA001J0Z

Ledipasvir (acetone)

CAS: 1441674-54-9

Ledipasvir (acetone) (GS-5885 acetone) is an HCV NS5A polymerase inhibitor, used for the treatment of hepatitis C virus infection.

Formula: C₅₂H₆₀F₂N₈O₇

Purity: 99.72%

Color and Shape: Solid

Molecular weight: 947.08

Ref: TM-T4203

Ledipasvir (acetone)

Controlled Product

CAS: 1441674-54-9

Ledipasvir is a synthetic antiviral agent. It is an oral prodrug that is converted to solvates in the liver and then hydrolyzed to the active form, ledipasvir (acetone). Ledipasvir inhibits hepatitis C virus by binding to NS5A, a nonstructural protein of the virus. Ledipasvir does not have activity against other viruses such as HIV-1 or influenza A virus. Ledipasvir has been shown to be well-tolerated in clinical trials with few side effects. Ledipasvir is used for the treatment of chronic hepatitis C infection.

Formula: C₅₂H₆₀F₂N₈O₇

Purity: Min. 95%

Molecular weight: 947.08 g/mol

Ref: 3D-RHC67454