CAS 144177-30-0

(1R,3aS,3bR,5aS,15aS,15bS,17aS)-1-Ethynyl-2,3,3a,3b,4,5,5a,6,15,15a,15b,16,17,17a-tetradecahydro-15a,17a-dimethyl-1H-benzimidazo[2,1-b]cyclopenta[5,6]naphtho[1,2-g]quinazolin-1-ol

Description:

The chemical substance with the name "(1R,3aS,3bR,5aS,15aS,15bS,17aS)-1-Ethynyl-2,3,3a,3b,4,5,5a,6,15,15a,15b,16,17,17a-tetradecahydro-15a,17a-dimethyl-1H-benzimidazo[2,1-b]cyclopenta[5,6]naphtho[1,2-g]quinazolin-1-ol" and CAS number "144177-30-0" is a complex organic compound characterized by its intricate polycyclic structure and multiple stereocenters, which contribute to its specific three-dimensional configuration. This compound features an ethynyl group, indicating the presence of a carbon-carbon triple bond, and contains a benzimidazole moiety, which is known for its biological activity. The presence of multiple fused rings suggests potential hydrophobic characteristics, which may influence its solubility and interaction with biological systems. Additionally, the compound's stereochemistry may play a crucial role in its pharmacological properties, potentially affecting receptor binding and activity. Overall, this substance is of interest in medicinal chemistry, particularly for its potential therapeutic applications, although specific biological activities would require further investigation.

Formula: C₂₉H₃₃N₃O

InChI: InChI=1S/C29H33N3O/c1-4-29(33)14-12-22-20-10-9-19-15-24-18(16-27(19,2)21(20)11-13-28(22,29)3)17-32-25-8-6-5-7-23(25)30-26(32)31-24/h1,5-8,17,19-22,33H,9-16H2,2-3H3/t19-,20+,21-,22-,27-,28-,29-/m0/s1

InChI key: InChIKey=AIIXYCDTEGICEE-HZVAOYAWSA-N

SMILES: C[C@@]12[C@@]3([C@]([C@]4([C@](C)(CC3)[C@@](C#C)(O)CC4)[H])(CC[C@]1(CC=5C(C2)=CN6C(N5)=NC=7C6=CC=CC7)[H])[H])[H]

Synonyms:

• (1R,3aS,3bR,5aS,15aS,15bS,17aS)-1-Ethynyl-2,3,3a,3b,4,5,5a,6,15,15a,15b,16,17,17a-tetradecahydro-15a,17a-dimethyl-1H-benzimidazo[2,1-b]cyclopenta[5,6]naphtho[1,2-g]quinazolin-1-ol
• 1H-Benzimidazo[2,1-b]cyclopenta[5,6]naphtho[1,2-g]quinazolin-1-ol, 1-ethynyl-2,3,3a,3b,4,5,5a,6,15,15a,15b,16,17,17a-tetradecahydro-15a,17a-dimethyl-, (1R,3aS,3bR,5aS,15aS,15bS,17aS)-
• 1H-Benzimidazo[2,1-b]cyclopenta[5,6]naphtho[1,2-g]quinazolin-1-ol, 1-ethynyl-2,3,3a,3b,4,5,5a,6,15,15a,15b,16,17,17a-tetradecahydro-15a,17a-dimethyl-, [1R-(1α,3aβ,3bα,5aβ,15aα,15bβ,17aα)]-
• WIN 51708 hydrate
• Win 51708

WIN 51,708

CAS: 144177-30-0

WIN 51,708

Purity: ≥98%

Molecular weight: 439.59g/mol

Ref: 54-BUP00269

WIN 51708 hydrate

CAS: 144177-30-0

Formula: C₂₉H₃₃N₃O·xH₂O

Molecular weight: 439.59 (anhydrous)

Ref: 7W-GK9657

WIN 51,708

CAS: 144177-30-0

WIN 51,708 is an antagonist of neurokinin-1 receptor.

Formula: C₂₉H₃₃N₃O

Purity: 99%

Color and Shape: Solid

Molecular weight: 439.59

Ref: TM-T29157

Win 51708 hydrate

CAS: 144177-30-0

Win 51708 is a dopamine agonist that binds to the D1 and D2 receptors in the rat striatal region. The drug has dose-dependent effects, with low doses inducing a decrease of acetylcholine release, while high doses induce an increase in acetylcholine release. Win 51708 also interacts with the antinociceptive properties of camp and inhibits bladder contractions induced by neurokinin-1 receptor activation.

Formula: C₂₉H₃₃N₃O

Purity: Min. 95%

Molecular weight: 439.6 g/mol

Ref: 3D-UFA17730