CAS 1443118-44-2

[2-Fluoro-4-[2-(4-methoxyphenyl)ethynyl]phenyl][(3R)-3-hydroxy-1-piperidinyl]methanone

CAS: 1443118-44-2

Formula: C₂₁H₂₀FNO₃

Purity: 95%

Color and Shape: Solid

Molecular weight: 353.3868

Ref: IN-DA01ENN9

ML337

CAS: 1443118-44-2

ML337

Purity: ≥98%

Molecular weight: 353.39g/mol

Ref: 54-BUP08275

ML 337

CAS: 1443118-44-2

ML337 is a functional ligand that binds to the metabotropic glutamate receptor subtype 2 (mGlu2). It has been shown to be an allosteric modulator of mGlu2, where it acts as an agonist at low concentrations and as a negative allosteric modulator at high concentrations. ML337 has been shown to inhibit calcium-sensing receptor function in renal cells and may have potential for the treatment of chronic kidney diseases.

Formula: C₂₁H₂₀FNO₃

Purity: Min. 95%

Molecular weight: 353.4 g/mol

Ref: 3D-THC11844

ML337

CAS: 1443118-44-2

ML337 is a negative allosteric modulator of mGlu3 with an IC50 of 593 nM.

Formula: C₂₁H₂₀FNO₃

Purity: 99.83%

Color and Shape: Solid

Molecular weight: 353.39

Ref: TM-T23003