CAS 1443138-53-1

GSK2200150A

CAS: 1443138-53-1

GSK2200150A

Purity: ≥98%

Molecular weight: 357.47g/mol

Ref: 54-BUP10350

GSK2200150A

CAS: 1443138-53-1

GSK2200150A is an anti-tuberculosis (TB) agent identified by high-throughput screening (HTS) campaign.

Formula: C₂₀H₂₃NO₃S

Purity: 99.14% - 99.16%

Color and Shape: Solid

Molecular weight: 357.47

Ref: TM-T4531

GSK2200150A

CAS: 1443138-53-1

GSK2200150A is a chemically synthesized compound that has been shown to have potent antitubercular activity against drug-resistant strains. GSK2200150A was developed from the naturally occurring sugar trehalose, which has been shown to be an excellent substrate for microbial glycosylation. GSK2200150A inhibits the synthesis of mycolic acids in mycobacteria and prevents the formation of periplasmic granules, two virulence factors that are important in tuberculosis. GSK2200150A also inhibits protein synthesis by inhibiting the activity of ribosomes, which are responsible for protein production. The structure-activity relationship (SAR) of this compound indicates that it is a potent inhibitor of Mycobacterium tuberculosis and may be useful as a treatment for drug-resistant strains.

Formula: C₂₀H₂₃NO₃S

Purity: Min. 95%

Molecular weight: 357.47 g/mol

Ref: 3D-THC13853