CAS 144337-18-8

1,1'-{2,4,6-trihydroxy-5-[7-hydroxy-2-(4-hydroxyphenyl)-3,4-dihydro-2H-chromen-4-yl]benzene-1,3-diyl}didodecan-1-one

Description:

The chemical substance known as "1,1'-{2,4,6-trihydroxy-5-[7-hydroxy-2-(4-hydroxyphenyl)-3,4-dihydro-2H-chromen-4-yl]benzene-1,3-diyl}didodecan-1-one," with the CAS number 144337-18-8, is a complex organic compound characterized by its multi-functional structure. It features a dodecanone backbone, which contributes to its hydrophobic properties, while the presence of multiple hydroxyl groups indicates significant polarity and potential for hydrogen bonding. The compound also contains chromene and phenolic moieties, suggesting potential antioxidant activity and interactions with biological systems. Its intricate structure may allow for various applications in fields such as pharmaceuticals, where it could serve as a lead compound for drug development or as a functional ingredient in cosmetic formulations. The presence of multiple functional groups also implies that it may exhibit diverse chemical reactivity, making it a subject of interest for further research in organic synthesis and medicinal chemistry. Overall, this compound exemplifies the complexity and versatility often found in organic molecules with potential therapeutic applications.

Formula: C₄₅H₆₂O₈

InChI: InChI=1/C45H62O8/c1-3-5-7-9-11-13-15-17-19-21-36(48)41-43(50)40(44(51)42(45(41)52)37(49)22-20-18-16-14-12-10-8-6-4-2)35-30-38(31-23-25-32(46)26-24-31)53-39-29-33(47)27-28-34(35)39/h23-29,35,38,46-47,50-52H,3-22,30H2,1-2H3

SMILES: CCCCCCCCCCCC(=O)c1c(c(C2CC(c3ccc(cc3)O)Oc3cc(ccc23)O)c(c(C(=O)CCCCCCCCCCC)c1O)O)O

Synonyms:

• 1,1'-{2,4,6-Trihydroxy-5-[7-hydroxy-2-(4-hydroxyphenyl)-3,4-dihydro-2H-chromen-4-yl]-1,3-phenylene}didodecan-1-one
• 1-Dodecanone, 1,1'-(5-(3,4-dihydro-7-hydroxy-2-(4-hydroxyphenyl)-2H-1-benzopyran-4-yl)-2,4,6-trihydroxy-1,3-phenylene)bis-
• 4-(3,5-Didodecanoyl-2,4,6-trihydroxyphenyl)-7-hydroxy-2-(4-hydroxyphenyl)chroman

1-Dodecanone, 1,1'-[5-[3,4-dihydro-7-hydroxy-2-(4-hydroxyphenyl)-2H-1-benzopyran-4-yl]-2,4,6-trihydroxy-1,3-phenylene]bis-

CAS: 144337-18-8

Formula: C₄₅H₆₂O₈

Purity: 98%

Molecular weight: 730.9690

Ref: IN-DA001JD4

YM 26734

CAS: 144337-18-8

YM 26734 is a fatty acid that has been shown to inhibit the activity of secretory phospholipase A2 (sPLA2). This enzyme is responsible for releasing arachidonic acid from membrane phospholipids, which can then be converted into pro-inflammatory molecules. YM 26734 inhibits sPLA2 by binding to its active site and preventing the conversion of arachidonic acid to inflammatory molecules. It also prevents the activation of inflammation-inducing enzymes, such as cyclooxygenase 2 and 5 lipoxygenase. YM 26734 has been shown to have a clinical relevance in the treatment of dental caries and periodontal disease. The effective dose for this drug has not yet been established.

Formula: C₄₅H₆₂O₈

Purity: Min. 95%

Molecular weight: 730.97 g/mol

Ref: 3D-UFA33718

YM 26734

CAS: 144337-18-8

Competitive inhibitor of secretory phospholipase A2 (sPLA2)

Formula: C₄₅H₆₂O₈

Purity: 98%

Color and Shape: Solid

Molecular weight: 730.97

Ref: TM-T23547