AM-2099, identified by its CAS number 1443373-17-8, is a synthetic compound that belongs to a class of substances known for their potential pharmacological properties. While specific characteristics such as its molecular formula, structure, and detailed physical properties may not be widely documented, compounds in this category are often studied for their interactions with biological systems, particularly in the context of neuroscience or pharmacology. Typically, such substances may exhibit properties like solubility in organic solvents, varying degrees of stability under different conditions, and specific reactivity profiles. The compound may also be evaluated for its efficacy and safety in preclinical or clinical studies, depending on its intended application. As with any chemical substance, understanding its characteristics requires careful consideration of its synthesis, mechanism of action, and potential therapeutic uses, alongside any regulatory or safety information pertinent to its handling and application.

AM-2099 is a potent and selective NaV1.7 Inhibitor (hNav1.7 IC50 = 0.16 uM; hNav1.5 IC50 > 30 uM; Papp = 31 x 10 (-6)cm/s; Rat IV CL (b/h/kg) \= 0.54; cLogD = 2.1). AM-2099 demonstrated a favorable pharmacokinetic profile in rat and dog and demonstrated dose-dependent reduction of histamine-induced scratching bouts in a mouse behavioral model following oral dosing.

AM-2099

1443373-17-8: AM-2099, identified by its CAS number 1443373-17-8, is a synthetic compound that belongs to a class of substances known for their potential pharmacological properties. While specific characteristics such as its molecular formula, structure, and detailed physical properties may not be widely documented, compounds in this category are often studied for their interactions with biological systems, particularly in the context of neuroscience or pharmacology. Typically, such substances may exhibit properties like solubility in organic solvents, varying degrees of stability under different conditions, and specific reactivity profiles. The compound may also be evaluated for its efficacy and safety in preclinical or clinical studies, depending on its intended application. As with any chemical substance, understanding its characteristics requires careful consideration of its synthesis, mechanism of action, and potential therapeutic uses, alongside any regulatory or safety information pertinent to its handling and application.

AM-2099 is a selective voltage-gated sodium channel Nav1.7 inhibitor used in pain research.

<p>AM-2099 is a research tool that has been shown to activate the receptor for substance P. AM-2099 is a ligand that binds to the receptor for substance P and activates it, which leads to an increase in intracellular calcium ion levels. AM-2099 has also been shown to inhibit ion channels and cell biology, as well as binding with antibodies and peptides. This compound is used in pharmacology and life science research.</p>

CAS 1443373-17-8

AM-2099

AM-2099

Ref: TM-T14201

AM-2099

Ref: 3D-THC37317