Benzyl-PEG4-CH2CO2tBu, with the CAS number 1443467-88-6, is a chemical compound that belongs to the class of polyethylene glycol (PEG) derivatives. This substance features a benzyl group, a four-unit polyethylene glycol chain, and a tert-butyl ester of acetic acid. The presence of the PEG moiety imparts hydrophilicity, enhancing solubility in aqueous environments, while the benzyl group contributes to its lipophilicity, allowing for versatile applications in drug delivery and bioconjugation. The tert-butyl ester provides stability and can be hydrolyzed under specific conditions, making it useful in controlled release formulations. Additionally, the compound's structure allows for functionalization, enabling the attachment of various biomolecules or drugs, which is advantageous in the development of targeted therapies. Overall, Benzyl-PEG4-CH2CO2tBu is characterized by its amphiphilic nature, biocompatibility, and potential for modification, making it a valuable tool in pharmaceutical and biomedical research.

Benzyl-PEG4-CH2CO2tBu is a PEG linker with a benzyl and t-butyl protecting group. Both protecting groups are acid labile. The hydrophilic PEG linker increases the water solubility of the compound in aqueous media.

Benzyl-PEG4-CH2CO2tBu

1443467-88-6: Benzyl-PEG4-CH2CO2tBu, with the CAS number 1443467-88-6, is a chemical compound that belongs to the class of polyethylene glycol (PEG) derivatives. This substance features a benzyl group, a four-unit polyethylene glycol chain, and a tert-butyl ester of acetic acid. The presence of the PEG moiety imparts hydrophilicity, enhancing solubility in aqueous environments, while the benzyl group contributes to its lipophilicity, allowing for versatile applications in drug delivery and bioconjugation. The tert-butyl ester provides stability and can be hydrolyzed under specific conditions, making it useful in controlled release formulations. Additionally, the compound's structure allows for functionalization, enabling the attachment of various biomolecules or drugs, which is advantageous in the development of targeted therapies. Overall, Benzyl-PEG4-CH2CO2tBu is characterized by its amphiphilic nature, biocompatibility, and potential for modification, making it a valuable tool in pharmaceutical and biomedical research.

<p>Benzyl-PEG3-CH2-Boc is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules.</p>

CAS 1443467-88-6

Benzyl-PEG4-CH2CO2tBu

Benzyl-PEG3-CH2-Boc

Ref: TM-T14537

Benzyl-PEG4-CH2CO2tBu

Ref: 54-BIPG1192