CAS 144371-88-0

Formula: C51H82N8O21S

InChI: InChI=1S/C51H82N8O21S/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-17-37(66)53-30-22-34(64)47(72)57-49(74)41-42(67)26(2)24-59(41)51(76)39(33(63)23-36(52)65)55-48(73)40(44(69)43(68)28-18-19-32(62)35(20-28)80-81(77,78)79)56-46(71)31-21-29(61)25-58(31)50(75)38(27(3)60)54-45(30)70/h18-20,26-27,29-31,33-34,38-44,47,60-64,67-69,72H,4-17,21-25H2,1-3H3,(H2,52,65)(H,53,66)(H,54,70)(H,55,73)(H,56,71)(H,57,74)(H,77,78,79)/t26-,27+,29+,30-,31-,33+,34+,38-,39-,40-,41-,42-,43-,44-,47+/m0/s1

InChI key: KAPLTEIQCKDUAT-UYCSHIFKSA-N

SMILES: CCCCCCCCCCCCCCCC(=O)N[C@H]1C[C@H]([C@H](NC(=O)[C@@H]2[C@H]([C@H](CN2C(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H]3C[C@H](CN3C(=O)[C@@H](NC1=O)[C@@H](C)O)O)[C@@H]([C@H](C4=CC(=C(C=C4)O)OS(=O)(=O)O)O)O)[C@@H](CC(=O)N)O)C)O)O)O

1-[(4R,5R)-4,5-Dihydroxy-N2-(1-oxohexadecyl)-L-ornithine]-4-[(4S)-4-hydroxy-4-[4-hydroxy-3-(sulfooxy)phenyl]-L-threonine]-pneumocandin A0

CAS: 144371-88-0

1-[(4R,5R)-4,5-Dihydroxy-N2-(1-oxohexadecyl)-L-ornithine]-4-[(4S)-4-hydroxy-4-[4-hydroxy-3-(sulfooxy)phenyl]-L-threonine]-pneumocandin A0

Formula: C₅₁H₈₂N₈O₂₁S

Purity: ≥95%

Molecular weight: 1175.3

Ref: 54-OR1112029

1-[(4R,5R)-4,5-Dihydroxy-N2-(1-oxohexadecyl)-L-ornithine]-4-[(4S)-4-hydroxy-4-[4-hydroxy-3-(sulfooxy)phenyl]-L-threonine]-pneumocandin A0

CAS: 144371-88-0

Formula: C₅₁H₈₂N₈O₂₁S

Purity: 90%

Color and Shape: Solid

Molecular weight: 1175.3028

Ref: IN-DA001JF2

FR901379

CAS: 144371-88-0

FR901379, an echinocandin-like antifungal, combats various fungi, protects mice from C. albicans, and lessens P. carinii infection symptoms.

Formula: C₅₁H₈₂N₈O₂₁S

Color and Shape: Solid

Molecular weight: 1175.31

Ref: TM-T35700

Micafungin Impurity FR-901379

CAS: 144371-88-0

Formula: C₅₁H₈₂N₈O₂₁S

Color and Shape: Off-White Solid

Molecular weight: 1175.31

Ref: 4Z-PM-127012

FR901379

CAS: 144371-88-0

Ref: BE-RMCP507012

FR 901379

CAS: 144371-88-0

FR 901379 is a new echinocandin drug that has been developed to treat Candida infections. It is a cyclic lipopeptide that inhibits the synthesis of ergosterol, an important component of fungal cell membranes. FR 901379 binds to the sterols in the membrane and alters its permeability, leading to cell death. This drug has been shown to have a low toxicity profile and can be administered orally with no need for intravenous administration. FR 901379 is structurally related to micafungin, but it differs from micafungin in that it is not acid-labile and it does not bind to DNA.

Formula: C₅₁H₈₂N₈O₂₁S

Purity: Min. 95%

Molecular weight: 1,175.3 g/mol

Ref: 3D-UFA37188

FR 901379 (>90%)

Controlled Product

CAS: 144371-88-0

Applications FR 901379 is an impurity of Micafungin (M342350), a lipopeptide compound that acts as an antifungal agent with activity against Aspergillus and Candida species.
References Denning, D., et al.: J. Infection, 53, 337 (2006); Queiroz-Telles, F., et al.: Pediatr. Infect. Dis. J., 27, 820 (2008)

Formula: C₅₁H₈₂N₈O₂₁S

Purity: >90%

Color and Shape: Neat

Molecular weight: 1175.3

Ref: TR-F763300

Micafungin FR 901379

CAS: 144371-88-0

Formula: C₅₁H₈₂N₈O₂₁S

Molecular weight: 1175.3

Ref: ST-EA-CP-M94016