CAS 144379-26-0

napsamycin C

Description:

Napsamycin C is a natural product belonging to the class of macrolide antibiotics, which are known for their broad-spectrum antibacterial properties. It is derived from the fermentation of specific strains of Streptomyces bacteria. Napsamycin C exhibits a complex molecular structure characterized by a large lactone ring, which is typical of macrolides, and contains multiple functional groups that contribute to its biological activity. This compound has shown potential in inhibiting the growth of various pathogenic bacteria and may also possess antitumor properties, making it a subject of interest in pharmaceutical research. Its mechanism of action typically involves interference with bacterial protein synthesis, although specific pathways may vary. Additionally, the compound's solubility, stability, and bioavailability are important factors that influence its therapeutic efficacy. As with many natural products, the extraction and purification processes can be challenging, and ongoing studies aim to optimize these methods for potential clinical applications. Overall, napsamycin C represents a promising candidate in the search for new antimicrobial agents.

Formula: C₃₉H₅₀N₈O₁₂S

InChI: InChI=1/C39H50N8O12S/c1-20(46(2)35(54)28-16-23-15-25(49)8-7-22(23)18-40-28)32(34(53)41-19-26-17-30(50)36(59-26)47-11-9-31(51)44-39(47)58)45-33(52)27(10-12-60-3)42-38(57)43-29(37(55)56)14-21-5-4-6-24(48)13-21/h4-8,13,15,19-20,27-30,32,36,40,48-50H,9-12,14,16-18H2,1-3H3,(H,41,53)(H,45,52)(H,55,56)(H2,42,43,57)(H,44,51,58)/b26-19-

Synonyms:

• Napsamycin C
• N-{[1-{[1-({(Z)-[5-(2,4-dioxotetrahydropyrimidin-1(2H)-yl)-4-hydroxydihydrofuran-2(3H)-ylidene]methyl}carbamoyl)-2-{[(6-hydroxy-1,2,3,4-tetrahydroisoquinolin-3-yl)carbonyl](methyl)amino}propyl]carbamoyl}-3-(methylsulfanyl)propyl]carbamoyl}-3-hydroxyphenylalanine

Napsamycin C

CAS: 144379-26-0

Napsamycin C is an antibiotic with antibacterial activity against Pseudomonas aeruginosa and other Pseudomonas species; however, it exhibits relatively weak antibacterial activity against other Gram-positive and Gram-negative bacteria.

Formula: C₃₉H₅₀N₈O₁₂S

Color and Shape: Solid

Molecular weight: 854.926

Ref: TM-TN10377