Amyloid-beta protein (1-40) is a peptide that plays a significant role in the pathogenesis of Alzheimer's disease. This specific variant, derived from mouse and rat sources, consists of 40 amino acids and is a fragment of the larger amyloid precursor protein (APP). The protein is characterized by its propensity to aggregate into oligomers and fibrils, which are associated with neurotoxicity and the formation of amyloid plaques in the brain. Its structure includes hydrophobic regions that facilitate aggregation, and it exhibits a high degree of beta-sheet content in its fibrillar form. The CAS number 144409-98-3 uniquely identifies this peptide, which is often used in research to study Alzheimer's disease mechanisms and to develop potential therapeutic strategies. In laboratory settings, it is typically synthesized for experimental purposes, and its behavior can be influenced by factors such as pH, temperature, and the presence of metal ions. Understanding the properties and interactions of amyloid-beta is crucial for advancing knowledge in neurodegenerative diseases.

Amyloid-beta Protein (1-40), mouse, rat

144409-98-3: Amyloid-beta protein (1-40) is a peptide that plays a significant role in the pathogenesis of Alzheimer's disease. This specific variant, derived from mouse and rat sources, consists of 40 amino acids and is a fragment of the larger amyloid precursor protein (APP). The protein is characterized by its propensity to aggregate into oligomers and fibrils, which are associated with neurotoxicity and the formation of amyloid plaques in the brain. Its structure includes hydrophobic regions that facilitate aggregation, and it exhibits a high degree of beta-sheet content in its fibrillar form. The CAS number 144409-98-3 uniquely identifies this peptide, which is often used in research to study Alzheimer's disease mechanisms and to develop potential therapeutic strategies. In laboratory settings, it is typically synthesized for experimental purposes, and its behavior can be influenced by factors such as pH, temperature, and the presence of metal ions. Understanding the properties and interactions of amyloid-beta is crucial for advancing knowledge in neurodegenerative diseases.

Amyloid β-Protein (1-40) (mouse, rat)

<p>Rat form of the beta-Amyloid (1-40) peptide</p>

β-Amyloid (1-40) (rat)

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CAS 144409-98-3

Amyloid-beta Protein (1-40), mouse, rat

Amyloid β-Protein (1-40) (mouse, rat)

Ref: 01-4035886

β-Amyloid (1-40) (rat)

Ref: TM-TP1441

Amyloid β-Protein (1-40) (mouse, rat)

Ref: 3D-FA109563