CAS 144412-49-7

Lamifiban

Description:

Lamifiban is a synthetic compound classified as a non-peptide antagonist of the glycoprotein IIb/IIIa receptor, which plays a crucial role in platelet aggregation. It is primarily investigated for its potential use in preventing thrombotic events in cardiovascular diseases. Lamifiban exhibits high affinity for the glycoprotein IIb/IIIa receptor, thereby inhibiting platelet aggregation and reducing the risk of clot formation. The substance is typically administered in a clinical setting, often in conjunction with other antiplatelet therapies. Its pharmacokinetic profile suggests a rapid onset of action, although the specifics can vary based on formulation and administration route. Lamifiban's efficacy and safety profile have been evaluated in various clinical trials, contributing to its understanding as a therapeutic agent. As with many pharmacological agents, potential side effects may include bleeding complications, which necessitate careful monitoring during treatment. Overall, Lamifiban represents a significant advancement in antithrombotic therapy, particularly for patients at high risk of cardiovascular events.

Formula: C₂₄H₂₈N₄O₆

InChI: InChI=1/C24H28N4O6/c25-22(26)16-3-5-17(6-4-16)23(32)27-20(13-15-1-7-18(29)8-2-15)24(33)28-11-9-19(10-12-28)34-14-21(30)31/h1-8,19-20,29H,9-14H2,(H3,25,26)(H,27,32)(H,30,31)/t20-/m0/s1

InChI key: InChIKey=FPKOGTAFKSLZLD-FQEVSTJZSA-N

SMILES: [C@@H](C(=O)N1CCC(OCC(O)=O)CC1)(CC2=CC=C(O)C=C2)NC(=O)C3=CC=C(C(=N)N)C=C3

Synonyms:

• Acetic acid, [[1-[2-[[4-(aminoiminomethyl)benzoyl]amino]-3-(4-hydroxyphenyl)-1-oxopropyl]-4-piperidinyl]oxy]-, (S)-
• Acetic acid, [[1-[(2S)-2-[[4-(aminoiminomethyl)benzoyl]amino]-3-(4-hydroxyphenyl)-1-oxopropyl]-4-piperidinyl]oxy]-
• Acetic acid, 2-[[1-[(2S)-2-[[4-(aminoiminomethyl)benzoyl]amino]-3-(4-hydroxyphenyl)-1-oxopropyl]-4-piperidinyl]oxy]-
• Ro 44-9883
• 2-[[1-[(2S)-2-[[4-(Aminoiminomethyl)benzoyl]amino]-3-(4-hydroxyphenyl)-1-oxopropyl]-4-piperidinyl]oxy]acetic acid
• ({1-[N-(4-carbamimidoylbenzoyl)tyrosyl]piperidin-4-yl}oxy)acetic acid
• [(1-{N-[(4-carbamimidoylphenyl)carbonyl]-L-tyrosyl}piperidin-4-yl)oxy]acetic acid
• ({1-[N-(4-carbamimidoylbenzoyl)tyrosyl]piperidin-4-yl}oxy)aceticacid
• Ro-44-9883/000
• Ro 44-9883/000
• Ro44-9883/000

Lamifiban

CAS: 144412-49-7

Lamifiban is a nonpeptide glycoprotein IIb/IIIa antagonist. It prevents platelet loss during experimental cardiopulmonary bypass.

Formula: C₂₄H₂₈N₄O₆

Purity: 98%

Color and Shape: Solid

Molecular weight: 468.5

Ref: TM-T25607