CAS 144481-98-1: Landiolol hydrochloride

Description: Landiolol hydrochloride is a selective beta-1 adrenergic antagonist primarily used in clinical settings for its rapid onset and short duration of action, making it suitable for managing acute tachycardia and hypertension. It is a synthetic compound characterized by its ability to effectively lower heart rate and myocardial oxygen demand without significantly affecting peripheral vascular resistance. The substance is typically administered intravenously, allowing for precise control over dosing and immediate therapeutic effects. Its pharmacokinetic profile includes a rapid distribution phase and a short half-life, which necessitates continuous infusion for sustained effects. Landiolol hydrochloride is generally well-tolerated, with a side effect profile that may include hypotension and bradycardia. As with other beta-blockers, caution is advised in patients with pre-existing respiratory conditions or heart block. The compound's chemical structure features a unique arrangement that contributes to its selectivity and efficacy, making it a valuable tool in acute cardiovascular management.

Formula: C₂₅H₃₉N₃O₈·ClH

InChI: InChI=1S/C25H39N3O8.ClH/c1-25(2)35-18-22(36-25)17-34-23(30)8-5-19-3-6-21(7-4-19)33-16-20(29)15-26-9-10-27-24(31)28-11-13-32-14-12-28;/h3-4,6-7,20,22,26,29H,5,8-18H2,1-2H3,(H,27,31);1H/t20-,22+;/m0./s1

InChI key: InChIKey=DLPGJHSONYLBKP-IKGOIYPNSA-N

SMILES: Cl.O=C(OCC1OC(OC1)(C)C)CCC2=CC=C(OCC(O)CNCCNC(=O)N3CCOCC3)C=C2

Synonyms:

• Benzenepropanoic acid, 4-[(2S)-2-hydroxy-3-[[2-[(4-morpholinylcarbonyl)amino]ethyl]amino]propoxy]-, [(4S)-2,2-dimethyl-1,3-dioxolan-4-yl]methyl ester, hydrochloride (1:1)
• Benzenepropanoic acid, 4-[(2S)-2-hydroxy-3-[[2-[(4-morpholinylcarbonyl)amino]ethyl]amino]propoxy]-, [(4S)-2,2-dimethyl-1,3-dioxolan-4-yl]methyl ester, monohydrochloride
• Benzenepropanoic acid, 4-[2-hydroxy-3-[[2-[(4-morpholinylcarbonyl)amino]ethyl]amino]propoxy]-, (2,2-dimethyl-1,3-dioxolan-4-yl)methyl ester, monohydrochloride, [S-(R*,R*)]-
• Corebeta
• ONO 1101 hydrochloride
• Onoact
• Rapibloc
• [(4S)-2,2-dimethyl-1,3-dioxolan-4-yl]methyl 3-(4-{[(2S)-2-hydroxy-3-({2-[(morpholin-4-ylcarbonyl)amino]ethyl}amino)propyl]oxy}phenyl)propanoate hydrochloride (1:1)
• [(4S)-2,2-dimethyl-1,3-dioxolan-4-yl]methyl 3-[4-[(2S)-2-hydroxy-3-[2-(morpholine-4-carbonylamino)ethylamino]propoxy]phenyl]propanoate hydrochloride
• Landiolol hydrochloride

Benzenepropanoic acid, 4-[(2S)-2-hydroxy-3-[[2-[(4-morpholinylcarbonyl)amino]ethyl]amino]propoxy]-, [(4S)-2,2-dimethyl-1,3-dioxolan-4-yl]methyl ester, hydrochloride (1:1)

CAS: 144481-98-1

• Formula: C₂₅H₄₀ClN₃O₈
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 546.0534

Landiolol hydrochloride

CAS: 144481-98-1

• Formula: C₂₅H₄₀ClN₃O₈
• Molecular weight: 546.05

Landiolol hydrochloride

CAS: 144481-98-1

• Purity: 99.9%
• Molecular weight: 546.05g/mol

Landiolol Hydrochloride

CAS: 144481-98-1

• Purity: 99%
• Molecular weight: 546.05g/mol

Landiolol hydrochloride

CAS: 144481-98-1

Landiolol hydrochloride (ONO-1101 hydrochloride) is an ultra-short-acting β1 selective adrenoceptor antagonist.

• Formula: C₂₅H₄₀ClN₃O₈
• Purity: 99.91%
• Color and Shape: White Crystalline Powder
• Molecular weight: 546.05

LANDIOLOL HYDROCHLORIDE

CAS: 144481-98-1

Applications Landiolol is an ultra-short acting beta blocker that is used to treat patients with …

• Formula: C₂₅H₃₉N₃O₈·ClH
• Color and Shape: Neat
• Molecular weight: 546.05

((S)-2,2-DIMETHYL-1,3-DIOXOLAN-4-YL)METHYL 3-(4-((S)-2-HYDROXY-3-((2-(MORPHOLINE-4-CARBOXAMIDO)ETHYL)AMINO)PROPOXY)PHENYL)PROPANOATE HCL

CAS: 144481-98-1

• Purity: 97%
• Molecular weight: 546.0599975585938

Landiolol Hydrochloride

CAS: 133242-30-5 144481-98-1

• Formula: C₂₅H₃₉N₃O₈·HCl
• Purity: >98.0%(T)(HPLC)
• Color and Shape: White to Almost white powder to crystal
• Molecular weight: 546.06

Landiolol HCl

CAS: 144481-98-1

Landiolol hydrochloride is a cardiac agent that has been shown to increase the force of …

• Formula: C₂₅H₃₉N₃O₈·ClH
• Purity: Min. 95%
• Molecular weight: 546.05 g/mol