CAS 144490-73-3

Carbovir Monophosphate

Controlled Product

CAS: 144490-73-3

Impurity Abacavir - In House Impurity
Applications Carbovir Monophosphate (Abacavir - In House Impurity) is a phosphorylated metabolite of the human immunodeficiency virus inhibitor Carbovir (C177740). It is converted from Abacavir 5’-phosphate by the enzyme N6-Methyl-AMP aminohydrolase (1,2,3).
References (1) Murakami, E., et al.: J Med Chem. 25, 5902 (2011) (2) Vince, R.: Nucl. Acids Symp. Ser., 25, 193 (1991) (3) Schinkmanova, M. et al.: Biochem. Pharmacol., 71, 1370 (2006)

Formula: C₁₁H₁₄N₅O₅P

Color and Shape: Neat

Molecular weight: 327.23

Ref: TR-C177745

Carbovir monophosphate

CAS: 144490-73-3

Carbovir monophosphate is an antiviral agent, which is a metabolite derived from the prodrug abacavir. It functions as a nucleotide analog that interferes with viral replication. The source of Carbovir monophosphate is the metabolic conversion of abacavir, an antiretroviral medication used in the treatment of HIV. This conversion occurs primarily in the liver, facilitated by cellular enzymes.

Formula: C₁₁H₁₄N₅O₅P

Purity: Min. 95%

Molecular weight: 327.23 g/mol

Ref: 3D-UFA49073