CAS 144494-65-5
:Tirofiban
Description:
Tirofiban is a synthetic non-peptide antagonist of the glycoprotein IIb/IIIa receptor, primarily used in the medical field as an antiplatelet agent. It is indicated for the treatment of acute coronary syndromes and is often administered in conjunction with other antithrombotic therapies. Tirofiban works by inhibiting platelet aggregation, thereby reducing the risk of thrombus formation in patients with unstable angina or those undergoing percutaneous coronary interventions. The substance is typically administered intravenously and has a rapid onset of action, with effects lasting for several hours after discontinuation. Tirofiban is characterized by its relatively low molecular weight and specific binding affinity to the glycoprotein IIb/IIIa receptor, which is crucial for platelet aggregation. Its pharmacokinetics involve a short half-life, necessitating continuous infusion for sustained therapeutic effects. As with any medication, potential side effects include bleeding complications, which require careful monitoring during treatment. Overall, Tirofiban plays a significant role in the management of cardiovascular conditions, particularly in acute settings.
Formula:C22H36N2O5S
InChI:InChI=1S/C22H36N2O5S/c1-2-3-16-30(27,28)24-21(22(25)26)17-19-7-9-20(10-8-19)29-15-5-4-6-18-11-13-23-14-12-18/h7-10,18,21,23-24H,2-6,11-17H2,1H3,(H,25,26)/t21-/m0/s1
InChI key:InChIKey=COKMIXFXJJXBQG-NRFANRHFSA-N
SMILES:C([C@H](NS(CCCC)(=O)=O)C(O)=O)C1=CC=C(OCCCCC2CCNCC2)C=C1
Synonyms:- Aggrastat
- Tirofiban
- N-(Butylsulfonyl)-O-[4-(4-piperidinyl)butyl]-L-tyrosine
- MK-383
- N-(Butylsulfonyl)-O-[4-(4-piperidinyl)butyl]-L-tyrosine
- L-Tyrosine, N-(butylsulfonyl)-O-[4-(4-piperidinyl)butyl]-
- N-(butylsulfonyl)-O-[4-(piperidin-4-yl)butyl]-L-tyrosine
- Aggrestat
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Found 9 products.
L-Tyrosine, N-(butylsulfonyl)-O-[4-(4-piperidinyl)butyl]-
CAS:Formula:C22H36N2O5SPurity:98%Color and Shape:SolidMolecular weight:440.5966Tirofiban Hydrochloride Monohydrate
CAS:Formula:C22H36N2O5S·HCl·H2OPurity:>98.0%(HPLC)Color and Shape:White to Light yellow powder to crystalMolecular weight:495.08Tirofiban
CAS:Formula:C22H36N2O5SPurity:≥ 99.0%Color and Shape:Off-white powderMolecular weight:440.60Tirofiban
CAS:<p>Glycoprotein IIb/IIIa inhibitor; platelet aggregation inhibitor</p>Formula:C22H36N2O5SPurity:Min. 95%Color and Shape:PowderMolecular weight:440.6 g/molTirofiban
CAS:Tirofiban (L700462) (MK-383) is a selective palate GPIIb/IIIa antagonist which inhibits platelet aggregation with IC50 of 9 nM.Formula:C22H36N2O5SPurity:99.83%Color and Shape:SolidMolecular weight:440.6
![L-Tyrosine, N-(butylsulfonyl)-O-[4-(4-piperidinyl)butyl]-](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FIN%2Fthumb%2FDA001JME.jpg&w=3840&q=75)
