CAS 1445179-97-4

D-JNKI-1

CAS: 1445179-97-4

D-JNKI-1 (AM-111) is a highly effective and cell-permeable peptide inhibitor.

Formula: C₁₆₄H₂₈₆N₆₆O₄₀

Purity: 98%

Color and Shape: Solid

Molecular weight: 3822.44

Ref: TM-T10937

D-JNKI-1

CAS: 1445179-97-4

D-JNKI-1 is a synthetic peptide inhibitor, specifically targeting the c-Jun N-terminal kinase (JNK) pathway. It is developed from a human-derived sequence, incorporating a D-enantiomer configuration to enhance stability and resistance to proteolytic degradation. The mode of action involves the competitive inhibition of JNK's interaction with its substrates, effectively blocking the phosphorylation and subsequent activation of downstream targets. This inhibitory mechanism is achieved by binding directly to the JNK protein, preventing it from executing its usual signaling responsibilities.

Formula: C₁₆₄H₂₈₆N₆₆O₄₀

Purity: Min. 95%

Molecular weight: 3,822.4 g/mol

Ref: 3D-VHC17997