CAS 1445703-64-9

TFMB-(S)-2-HG

CAS: 1445703-64-9

TFMB-(S)-2-HG

Purity: ≥98%

Molecular weight: 288.22g/mol

Ref: 54-BUP12946

TFMB-(S)-2HG

CAS: 1445703-64-9

TFMB-(S)-2HG is a small molecule inhibitor, derived synthetically, which functions as a competitive antagonist of the α-ketoglutarate-dependent dioxygenases. This compound was originally designed to mimic the oncometabolite 2-hydroxyglutarate, thereby interfering with the normal enzymatic activity within the citric acid cycle and other related pathways. Its mode of action involves binding to the active site of target enzymes, displacing the α-ketoglutarate substrate, and subsequently inhibiting their catalytic activity.

Formula: C₁₃H₁₁F₃O₄

Purity: Min. 95%

Molecular weight: 288.22 g/mol

Ref: 3D-VHC70364

TFMB-(S)-2-HG

CAS: 1445703-64-9

TFMB-(S)-2-HG (TFMB S 2 HG) is a highly effective inhibitor of TET2, the 5'-methylcytosine hydroxylase.

Formula: C₁₃H₁₁F₃O₄

Purity: 98.07%

Color and Shape: Solid

Molecular weight: 288.22

Ref: TM-T24871