CAS 1445879-21-9

GSK2837808A

CAS: 1445879-21-9

GSK2837808A is a potent and selective inhibitor of lactate dehydrogenase A (LDHA) (IC50s: 1.9 and 14 nM for LDHA and LDHB, respectively).

Formula: C₃₁H₂₅F₂N₅O₇S

Purity: 99.78% - 99.78%

Color and Shape: Solid

Molecular weight: 649.62

Ref: TM-T15435

GSK2837808A

CAS: 1445879-21-9

Formula: C₃₁H₂₅F₂N₅O₇S

Purity: 98%

Color and Shape: Solid

Molecular weight: 649.6213

Ref: IN-DA01E24Z

GSK2837808A

CAS: 1445879-21-9

GSK2837808A

Purity: ≥98%

Molecular weight: 649.62g/mol

Ref: 54-BUP08741

3-((3-(N-Cyclopropylsulfamoyl)-7-(2,4-Dimethoxypyrimidin-5-Yl)Quinolin-4-Yl)Amino)-5-(3,5-Difluorophenoxy)Benzoic Acid

CAS: 1445879-21-9

3-((3-(N-Cyclopropylsulfamoyl)-7-(2,4-Dimethoxypyrimidin-5-Yl)Quinolin-4-Yl)Amino)-5-(3,5-Difluorophenoxy)Benzoic Acid

Purity: 98%

Molecular weight: 649.62g/mol

Ref: 54-PC108500

GSK2837808A

CAS: 1445879-21-9

Ref: 7W-GW7934

GSK 2837808A

CAS: 1445879-21-9

Formula: C₃₁H₂₅F₂N₅O₇S

Molecular weight: 649.14

Ref: 4Z-B-085007

3-((3-(N-Cyclopropylsulfamoyl)-7-(2,4-dimethoxypyrimidin-5-yl)quinolin-4-yl)amino)-5-(3,5-difluorophenoxy)benzoic acid

CAS: 1445879-21-9

Purity: 98%

Molecular weight: 649.630004882813

Ref: 10-F867169

GSK 2837808A

CAS: 1445879-21-9

GSK 2837808A is a small molecule that inhibits mitochondrial respiration and ATP synthesis. It binds to the mitochondrial receptor, which is found on the outer membrane of mitochondria. GSK 2837808A has been shown to inhibit tumor growth in deficient mice and human cancer cells, due to its ability to induce apoptosis by activating caspase-1. Inhibition of mitochondrial respiration may also have an effect on cellular energy metabolism, as well as epithelial mesenchymal transition. GSK 2837808A has also been shown to inhibit glutamate dehydrogenase, which can lead to decreased production of neurotransmitters such as dopamine and serotonin. GSK 2837808A also inhibits aerobic glycolysis in cancer cells, leading to a decrease in glucose uptake.

Purity: Min. 95%

Ref: 3D-BG170579