CAS 1446182-94-0

GDC-0917

Description:

GDC-0917, with the CAS number 1446182-94-0, is a small molecule that has been investigated primarily for its potential therapeutic applications in the treatment of various diseases, particularly in the context of cancer. It functions as a selective inhibitor of certain protein kinases, which play crucial roles in cell signaling pathways that regulate cell growth, proliferation, and survival. The compound's mechanism of action typically involves the modulation of specific targets within these pathways, leading to the inhibition of tumor cell proliferation and induction of apoptosis. GDC-0917 is characterized by its chemical structure, which includes specific functional groups that contribute to its biological activity and selectivity. Additionally, its pharmacokinetic properties, such as absorption, distribution, metabolism, and excretion, are essential for determining its efficacy and safety profile in clinical settings. Ongoing research continues to explore its potential in combination therapies and its effectiveness against various cancer types.

CUDC-427

CAS: 1446182-94-0

CUDC-427

Purity: ≥98%

Molecular weight: 564.7g/mol

Ref: 54-BUP08455

CUDC-427

CAS: 1446182-94-0

CUDC-427 is a small-molecule inhibitor of apoptosis proteins (IAP), which is a synthetic compound sourced from the design and synthesis of targeted anticancer agents. Its primary mode of action involves the selective inhibition of IAPs, particularly cIAP1 and cIAP2. This inhibition leads to the activation of caspases and subsequent induction of apoptosis in cancer cells.

Formula: C₂₉H₃₆N₆O₄S

Purity: Min. 95%

Molecular weight: 564.7 g/mol

Ref: 3D-WHC18294

CUDC-427

CAS: 1446182-94-0

CUDC-427 (GDC-0917) is an orally bioactive and pan antagonist of inhibitor of apoptosis proteins(IAPs). CUDC-427 can be used in research on cancers.

Formula: C₂₉H₃₆N₆O₄S

Purity: 99.92%

Color and Shape: Solid

Molecular weight: 564.7

Ref: TM-T15018