Bromo-PEG5-phosphonic acid is a chemical compound characterized by its unique structure, which includes a polyethylene glycol (PEG) chain with five ethylene glycol units, a bromine atom, and a phosphonic acid functional group. This compound is typically used in bioconjugation and drug delivery applications due to its hydrophilic nature, which enhances solubility in aqueous environments. The presence of the bromine atom allows for further functionalization, making it versatile for various chemical reactions. The phosphonic acid group contributes to its ability to form strong interactions with metal ions and surfaces, which is beneficial in applications such as surface modification and biomaterials. Additionally, the compound's stability and biocompatibility make it suitable for use in pharmaceutical formulations and research settings. Overall, Bromo-PEG5-phosphonic acid is a valuable tool in the fields of medicinal chemistry and materials science, facilitating the development of innovative therapeutic strategies and advanced materials.

Bromo-PEG5-phosphonic acid is a hydrophilic PEG linker containing a bromine group and a phosphonic acid group. The bromine is a good leaving group. The hydrophilic PEG chain increases the water solubility of compounds in aqueous media.

Bromo-PEG5-phosphonic acid

1446282-37-6: Bromo-PEG5-phosphonic acid is a chemical compound characterized by its unique structure, which includes a polyethylene glycol (PEG) chain with five ethylene glycol units, a bromine atom, and a phosphonic acid functional group. This compound is typically used in bioconjugation and drug delivery applications due to its hydrophilic nature, which enhances solubility in aqueous environments. The presence of the bromine atom allows for further functionalization, making it versatile for various chemical reactions. The phosphonic acid group contributes to its ability to form strong interactions with metal ions and surfaces, which is beneficial in applications such as surface modification and biomaterials. Additionally, the compound's stability and biocompatibility make it suitable for use in pharmaceutical formulations and research settings. Overall, Bromo-PEG5-phosphonic acid is a valuable tool in the fields of medicinal chemistry and materials science, facilitating the development of innovative therapeutic strategies and advanced materials.

Bromo-PEG5-phosphonic acid serves as a PEG-based PROTAC linker for the synthesis of PROTACs[1].

CAS 1446282-37-6

Bromo-PEG5-phosphonic acid

Bromo-PEG5-phosphonic acid

Ref: TM-T14810