CAS 1446502-11-9

2-Methyl-1-[[4-[6-(trifluoromethyl)-2-pyridinyl]-6-[[2-(trifluoromethyl)-4-pyridinyl]amino]-1,3,5-triazin-2-yl]amino]-2-propanol

Description:

2-Methyl-1-[[4-[6-(trifluoromethyl)-2-pyridinyl]-6-[[2-(trifluoromethyl)-4-pyridinyl]amino]-1,3,5-triazin-2-yl]amino]-2-propanol is a complex organic compound characterized by its multi-ring structure and the presence of trifluoromethyl groups, which enhance its lipophilicity and biological activity. The compound features a triazine core, which is known for its stability and utility in various chemical applications, particularly in pharmaceuticals and agrochemicals. The presence of pyridine rings contributes to its potential as a ligand in coordination chemistry and may influence its interaction with biological targets. Additionally, the hydroxyl group in the propanol moiety can participate in hydrogen bonding, affecting solubility and reactivity. This compound may exhibit significant biological activity, making it of interest in medicinal chemistry, particularly in the development of new therapeutic agents. Its specific properties, such as solubility, melting point, and reactivity, would depend on the molecular interactions and the environment in which it is studied.

Formula: C₁₉H₁₇F₆N₇O

InChI: InChI=1S/C19H17F6N7O/c1-17(2,33)9-27-15-30-14(11-4-3-5-12(29-11)18(20,21)22)31-16(32-15)28-10-6-7-26-13(8-10)19(23,24)25/h3-8,33H,9H2,1-2H3,(H2,26,27,28,30,31,32)

InChI key: InChIKey=DYLUUSLLRIQKOE-UHFFFAOYSA-N

SMILES: N(C1=NC(=NC(NCC(C)(C)O)=N1)C=2N=C(C(F)(F)F)C=CC2)C=3C=C(C(F)(F)F)N=CC3

Synonyms:

• 2-Propanol, 2-methyl-1-[[4-[6-(trifluoromethyl)-2-pyridinyl]-6-[[2-(trifluoromethyl)-4-pyridinyl]amino]-1,3,5-triazin-2-yl]amino]-
• AG 221
• 2-Methyl-1-(4-(6-(trifluoromethyl)pyridin-2-yl)-6-(2-(trifluoromethyl)pyridin-4-ylamino)-1,3,5-triazin-2-ylamino)propan-2-ol
• Enasidenib
• 2-Methyl-1-[[4-[6-(trifluoromethyl)-2-pyridinyl]-6-[[2-(trifluoromethyl)-4-pyridinyl]amino]-1,3,5-triazin-2-yl]amino]-2-propanol
• Enasidenib(AG-221)
• NameC
• AG-211
• AG221;AG 221
• AG-221 (Enasidenib)
• CS-1590

2-Propanol, 2-methyl-1-[[4-[6-(trifluoromethyl)-2-pyridinyl]-6-[[2-(trifluoromethyl)-4-pyridinyl]amino]-1,3,5-triazin-2-yl]amino]-

CAS: 1446502-11-9

Formula: C₁₉H₁₇F₆N₇O

Purity: 98%

Color and Shape: Solid

Molecular weight: 473.3750

Ref: IN-DA001JXC

Enasidenib

CAS: 1446502-11-9

Enasidenib

Purity: ≥98%

Molecular weight: 473.38g/mol

Ref: 54-BUP13309

Enasidenib

CAS: 1446502-11-9

Enasidenib (AG-221) is an orally available inhibitor of specific mutant forms of the mitochondrial enzyme isocitrate dehydrogenase type 2 (IDH2), with potential

Formula: C₁₉H₁₇F₆N₇O

Purity: 98% - >99.99%

Color and Shape: Solid

Molecular weight: 473.38

Ref: TM-T2346

Enasidenib

Controlled Product

CAS: 1446502-11-9

Formula: C₁₉H₁₇F₆N₇O

Color and Shape: Off-White

Molecular weight: 473.37

Ref: TR-E555360

AG 221

CAS: 1446502-11-9

Inhibitor of isocitrate dehydrogenase 2

Formula: C₁₉H₁₇F₆N₇O

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 473.38 g/mol

Ref: 3D-FA145490