CAS 144665-07-6

Lubeluzole

Description:

Lubeluzole, with the CAS number 144665-07-6, is a chemical compound primarily recognized for its neuroprotective properties. It is classified as a benzothiazole derivative and has been studied for its potential therapeutic applications, particularly in the treatment of neurodegenerative diseases. Lubeluzole exhibits a mechanism of action that involves modulation of glutamate receptors, which are crucial in neuronal signaling and can contribute to excitotoxicity when dysregulated. This compound is typically characterized by its ability to enhance neuronal survival and reduce cell death in various experimental models. Additionally, Lubeluzole has shown promise in improving cognitive function and has been investigated for its effects on conditions such as stroke and Alzheimer's disease. Its pharmacokinetic profile suggests good bioavailability, although specific details regarding its solubility and stability may vary based on formulation. Overall, Lubeluzole represents a significant area of interest in neuropharmacology, with ongoing research aimed at elucidating its full therapeutic potential and mechanisms of action.

Formula: C₂₂H₂₅F₂N₃O₂S

InChI: InChI=1S/C22H25F2N3O2S/c1-26(22-25-20-4-2-3-5-21(20)30-22)15-8-10-27(11-9-15)13-16(28)14-29-17-6-7-18(23)19(24)12-17/h2-7,12,15-16,28H,8-11,13-14H2,1H3/t16-/m0/s1

InChI key: InChIKey=OZFSWVOEXHGDES-INIZCTEOSA-N

SMILES: N(C)(C1=NC=2C(S1)=CC=CC2)C3CCN(C[C@@H](COC4=CC(F)=C(F)C=C4)O)CC3

Synonyms:

• (+)-(S)-4-(2-Benzothiazolylmethylamino)-a-((3,4-difluorophenoxy)methyl)-1-piperidineethanol
• (2S)-1-{4-[1,3-Benzothiazol-2-yl(methyl)amino]piperidin-1-yl}-3-(3,4-difluorophenoxy)propan-2-ol
• (aS)-4-(2-Benzothiazolylmethylamino)-a-[(3,4-difluorophenoxy)methyl]-1-piperidineethanol
• 1-Piperidineethanol, 4-(2-benzothiazolylmethylamino)-α-[(3,4-difluorophenoxy)methyl]-, (S)-
• 1-Piperidineethanol, 4-(2-benzothiazolylmethylamino)-α-[(3,4-difluorophenoxy)methyl]-, (αS)-
• 144665-07-6
• Prosynap
• R 86926
• R 87926
• Lubeluzole

Lubeluzole

CAS: 144665-07-6

Lubeluzole, a well-known neuroprotective agent, is recently proved useful to potentiate the activity of anti-cancer drugs.

Formula: C₂₂H₂₅F₂N₃O₂S

Purity: 98%

Color and Shape: Solid

Molecular weight: 433.51

Ref: TM-T25761