CAS 144678-63-7

NSC 668036 hydrate

CAS: 144678-63-7

Formula: C₂₁H₃₆N₂O₉·xH₂O

Molecular weight: 460.52 (anhydrous)

Ref: 7W-GK6389

NSC 668036

CAS: 144678-63-7

NSC 668036 is a natural compound with antitumor properties. It has been shown to inhibit the growth of tumor cells by altering cell signaling pathways. NSC 668036 blocks the signal transduction pathway of epidermal growth factor (EGF) and interferes with the activation of the downstream protein kinase, which inhibits the phosphorylation and inactivation of glycogen synthase kinase-3β (GSK-3β). This leads to a decrease in intracellular calcium levels, which has been shown to be associated with chemoresistance. In vitro studies have confirmed that NSC 668036 suppresses proliferation of colorectal cancer cells and inhibits metastasis as well as increased ATP levels.

Formula: C₂₁H₃₆N₂O₉

Purity: Min. 95%

Molecular weight: 460.52 g/mol

Ref: 3D-UFA67863

NSC-668036

CAS: 144678-63-7

NSC-668036 is an inhibitor of Dishevelled (Dvl) protein, a key protein in wnt signaling.

Formula: C₂₁H₃₆N₂O₉

Purity: 98%

Color and Shape: Solid

Molecular weight: 460.52

Ref: TM-T28211