CAS 144689-24-7
:Olmesartan
Description:
Olmesartan is an angiotensin II receptor antagonist primarily used in the treatment of hypertension. It belongs to the class of medications known as sartans, which work by blocking the action of angiotensin II, a hormone that causes blood vessels to constrict. This action leads to vasodilation, resulting in lowered blood pressure. Chemically, olmesartan is characterized by its complex structure, which includes a biphenyl group and a carboxylate moiety, contributing to its pharmacological activity. The substance is typically administered in the form of olmesartan medoxomil, a prodrug that is converted into its active form in the body. Olmesartan is known for its long half-life, allowing for once-daily dosing. It is generally well-tolerated, though potential side effects may include dizziness, headache, and gastrointestinal disturbances. As with other antihypertensive agents, it is important to monitor renal function and potassium levels during treatment. Overall, olmesartan is an effective option for managing high blood pressure and reducing the risk of cardiovascular events.
Formula:C24H26N6O3
InChI:InChI=1S/C24H26N6O3/c1-4-7-19-25-21(24(2,3)33)20(23(31)32)30(19)14-15-10-12-16(13-11-15)17-8-5-6-9-18(17)22-26-28-29-27-22/h5-6,8-13,33H,4,7,14H2,1-3H3,(H,31,32)(H,26,27,28,29)
InChI key:InChIKey=VTRAEEWXHOVJFV-UHFFFAOYSA-N
SMILES:C(N1C(C(O)=O)=C(C(C)(C)O)N=C1CCC)C2=CC=C(C=C2)C3=C(C=CC=C3)C=4NN=NN4
Synonyms:- 1H-Imidazole-5-carboxylic acid, 4-(1-hydroxy-1-methylethyl)-2-propyl-1-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-
- 1H-Imidazole-5-carboxylic acid, 4-(1-hydroxy-1-methylethyl)-2-propyl-1-[[2′-(2H-tetrazol-5-yl)[1,1′-biphenyl]-4-yl]methyl]-
- 1H-Imidazole-5-carboxylicacid, 4-(1-hydroxy-1-methylethyl)-2-propyl-1-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-
- 4-(1-Hydroxy-1-methylethyl)-2-propyl-1-[[2′-(2H-tetrazol-5-yl)[1,1′-biphenyl]-4-yl]methyl]-1H-imidazole-5-carboxylic acid
- Cs 088
- Olmesartan
- Olmetor
- Rnh 6270
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Found 16 products.
Olmesartan
CAS:Formula:C24H26N6O3Purity:>98.0%(HPLC)Color and Shape:White to Light yellow powder to crystalMolecular weight:446.511H-Imidazole-5-carboxylic acid, 4-(1-hydroxy-1-methylethyl)-2-propyl-1-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-
CAS:Formula:C24H26N6O3Purity:98%Color and Shape:SolidMolecular weight:446.50161-((2'-(1H-Tetrazol-5-Yl)-[1,1'-Biphenyl]-4-Yl)Methyl)-4-(2-Hydroxypropan-2-Yl)-2-Propyl-1H-Imidazole-5-Carboxylic Acid
CAS:<p>1-((2'-(1H-Tetrazol-5-Yl)-[1,1'-Biphenyl]-4-Yl)Methyl)-4-(2-Hydroxypropan-2-Yl)-2-Propyl-1H-Imidazole-5-Carboxylic Acid</p>Purity:98%Molecular weight:446.5g/molOlmesartan (Olmesartan Medoxomil EP Impurity A)
CAS:Formula:C24H26N6O3Color and Shape:White To Off-White SolidMolecular weight:446.51Olmesartan
CAS:Formula:C29H30N6O6Purity:(HPLC) ≥ 98.0%Color and Shape:White to off-white powderMolecular weight:558.59Olmesartan 100 µg/mL in Acetonitrile:Methanol
CAS:Controlled ProductFormula:C24H26N6O3Color and Shape:Single SolutionMolecular weight:446.504-(1-Hydroxy-1-methylethyl)-2-propyl-1-[[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]-1H-imidazole-5-carboxylic Acid (Olmesartan)
CAS:Controlled ProductFormula:C24H26N6O3Color and Shape:White To BeigeMolecular weight:446.50Olmesartan
CAS:<p>Olmesartan (RNH 6270) is an Angiotensin II Type I receptor antagonist.</p>Formula:C24H26N6O3Purity:91.89% - 99.81%Color and Shape:White To Beige Solid SolidMolecular weight:446.5Olmesartan Acid
CAS:Controlled Product<p>Impurity Olmesartan EP Impurity A<br>Applications Olmesartan Acid (Olmesartan EP Impurity A) is an angiotensin II receptor antagonist. Used as an anti-hypertensive.<br>References Yanagisawa, H., et al.: J. Med. Chem., 39, 323 (1996), Puchler, K., et al.: J. Hypertens., 15, 1809 (1997),<br></p>Formula:C24H26N6O3Color and Shape:White To BeigeMolecular weight:446.50Olmesartan
CAS:<p>Olmesartan medoxomil is a prodrug that is hydrolyzed to olmesartan, its active form. It is a member of the angiotensin II receptor antagonists and it is used for the treatment of hypertension and heart failure. Olmesartan medoxomil reduces the risk of cardiovascular events in patients with resistant hypertension or heart failure. The drug binds to the angiotensin II type 1 receptor, thereby blocking the binding of angiotensin II to this receptor. This prevents activation of downstream signaling pathways, including phospholipase C, protein kinase C, and mitogen-activated protein kinases. Olmesartan medoxomil also blocks the formation of new blood vessels and vascular remodeling in animal models.</p>Formula:C24H26N6O3Purity:Min. 95%Color and Shape:White PowderMolecular weight:446.5 g/mol
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