CAS 144689-63-4

olmesartan medoxomil

Description:

Olmesartan medoxomil is an angiotensin II receptor antagonist primarily used in the treatment of hypertension. It is a prodrug, meaning it is metabolized in the body to its active form, olmesartan. The substance is characterized by its ability to selectively block the angiotensin II type 1 (AT1) receptor, which plays a crucial role in regulating blood pressure and fluid balance. Chemically, olmesartan medoxomil is a white to off-white crystalline powder that is practically insoluble in water but soluble in organic solvents. Its molecular formula reflects a complex structure that includes a biphenyl group, contributing to its pharmacological activity. The compound exhibits a long half-life, allowing for once-daily dosing, and is often well-tolerated with a favorable side effect profile. Additionally, olmesartan medoxomil has been associated with renal protective effects, making it a valuable option in managing patients with hypertension, particularly those with comorbid conditions.

Formula: C₂₄H₂₆N₆O₃

InChI: InChI=1S/C29H30N6O6/c1-5-8-23-30-25(29(3,4)38)24(27(36)39-16-22-17(2)40-28(37)41-22)35(23)15-18-11-13-19(14-12-18)20-9-6-7-10-21(20)26-31-33-34-32-26/h6-7,9-14,38H,5,8,15-16H2,1-4H3,(H,31,32,33,34)

InChI key: InChIKey=UQGKUQLKSCSZGY-UHFFFAOYSA-N

SMILES: C(N1C(C(OCC2=C(C)OC(=O)O2)=O)=C(C(C)(C)O)N=C1CCC)C3=CC=C(C=C3)C4=C(C=CC=C4)C=5NN=NN5

Synonyms:

• (5-Methyl-2-oxo-1,3-dioxol-4-yl)methyl 4-(1-hydroxy-1-methylethyl)-2-propyl-1-[[2′-(2H-tetrazol-5-yl)[1,1′-biphenyl]-4-yl]methyl]-1H-imidazole-5-carboxylate
• (5-Methyl-2-oxo-1,3-dioxol-4-yl)methyl 4-(1-hydroxy-1-methylethyl)-2-propyl-1-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}imidazaole-5-carboxylate
• (5-Methyl-2-oxo-2H-1,3-dioxol-4-yl)methyl 4-(2-hydroxypropan-2-yl)-2-propyl-1-([4-[2-(1H-1,2,3,4-tetrazol-5-yl)phenyl]phenyl]methyl)-1H-imidazole-5-carboxylate
• (5-methyl-2-oxo-1,3-dioxol-4-yl)methyl 4-ethyl-2-propyl-1-{[2'-(2H-tetrazol-5-yl)biphenyl-4-yl]methyl}-1H-imidazole-5-carboxylate
• (5-methyl-2-oxo-1,3-dioxol-4-yl)methyl.5-(2-hydroxypropan-2-yl)-2-propyl-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]imidazole-4-carboxylate
• 1,3-Dioxole, 1H-imidazole-5-carboxylic acid deriv.
• 1H-Imidazole-5-Carboxylic Acid, 4-(1-Hydroxy-1-Methylethyl)-2-Propyl-1-[[2'-(1H-Tetrazol-5-Yl)[1,1'-Biphenyl]-4-Yl]Methyl]-, (5-Methyl-2-Oxo-1,3-Dioxol-4-Yl)Methyl Ester
• 1H-Imidazole-5-carboxylic acid, 4-(1-hydroxy-1-methylethyl)-2-propyl-1-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-, (5-methyl-2-oxo-1,3-dioxol-4-yl)methyl ester
• 2-Butyl-4-(1-hydroxy-1-methylethyl)-1-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H-imidazole-5-carboxylic acid (5-methyl-2-oxo-1,3-dioxol-4-yl)methyl ester
• 4-(1-Hydroxy-1-Methylethyl)-2-Propyl-1-[[2'-(1H-Tetazol-5-Yl)[1,1'-Biphenyl]-4-Yl]Methyl]-1H-Imidazole-5-Carboxylic Acid (5-Methyl-2-Oxo-1,3-Dioxol-4-Yl)Methyl Ester
• 4-(1-Hydroxy-1-Methylethyl)-2-Propyl-1-[[2'-(1H-Tetrazol-5-Yl)[1,1'-Biphenyl]-4-Yl]Methyl]-1H-Imidazole-5-Carboxylic Acid (5-Methyl-2-Oxo-1,3-Dioxol-4-Yl)Methyl Ester
• Angiosartan
• Benicar
• Cs-866
• Medoxomil
• Olmesartan Medoximil
• Olmetec
• Olsertain
• Omst
• Olmesartan medoxomil
• 5-(1-HYDROXY-1-METHYLETHYL)-2-PROPYL-3-[2''-(1H-TETRAZOL-5-YL)-BIPHENYL-4-YLMETHYL]-3H-IMIDAZOLE-4-CARBOXYLIC ACID 5-METHYL-2-OXO-[1,3]DIOXOL-4-YLMETHYL ESTER
• CS-866, 4-(1-Hydroxy-1-methylethyl)-2-propyl-1-[[2(1H-tetazol-5-yl)[1,1biphenyl]-4-yl]methyl]-1H-imidazole-5-carboxylic Acid (5-Methyl-2-oxo-1,3-dioxol-4-yl)methyl Ester
• 5-(1-Hydroxy-1-methylethyl)-2-propyl-3-[2'-(1H-tet
• OlmesartanC29H30N6O6
• OLMESARTAN
• 4-(1-Hydroxy-1-methylethyl)-2-propyl-1-[[2'-(1H-tetazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H-imidazole-5-carboxylicacid(5-Methyl-2-oxo-1,3-dioxol-4-yl)methylester

Olmesartan Medoxomil

CAS: 144689-63-4

Formula: C₂₉H₃₀N₆O₆

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 558.60

Ref: 3B-O0510

Olmesartan medoxomil

CAS: 144689-63-4

Olmesartan medoxomil

Formula: C₂₉H₃₀N₆O₆

Purity: 99.7%

Color and Shape: White. To. Light Yellow

Molecular weight: 558.22268

Ref: 47-1173

OLMESARTAN MEDOXOMIL CRS

CAS: 144689-63-4

OLMESARTAN MEDOXOMIL CRS

Formula: C₂₉H₃₀N₆O₆

Color and Shape: Powder

Molecular weight: 558.5851

Ref: 41-Y0001405

OLMESARTAN MEDOXOMIL FOR SYSTEM SUITABILITY CRS

CAS: 144689-63-4

OLMESARTAN MEDOXOMIL FOR SYSTEM SUITABILITY CRS

Formula: C₂₉H₃₀N₆O₆

Color and Shape: Powder

Molecular weight: 558.5851

Ref: 41-Y0001424

Olmesartan Medoxomil

CAS: 144689-63-4

Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoi

Formula: C₂₉H₃₀N₆O₆

Color and Shape: White Light Yellow Powder

Molecular weight: 558.22268

Ref: 45-1478367

Olmesartan Medoxomil

CAS: 144689-63-4

Olmesartan Medoxomil (Benicar) is an angiotensin II type 1 receptor blocker that is used to manage hypertension.

Formula: C₂₉H₃₀N₆O₆

Purity: 99.89% - 99.9%

Color and Shape: White To Off-White Crystalline Powder

Molecular weight: 558.59

Ref: TM-T1518

1H-Imidazole-5-carboxylic acid, 4-(1-hydroxy-1-methylethyl)-2-propyl-1-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-, (5-methyl-2-oxo-1,3-dioxol-4-yl)methyl ester

CAS: 144689-63-4

Formula: C₂₉H₃₀N₆O₆

Purity: 98%

Color and Shape: Solid

Molecular weight: 558.5851

Ref: IN-DA001K0D

Olmesartan Medoxomil

CAS: 144689-63-4

Olmesartan Medoxomil

Purity: 99%

Molecular weight: 558.59g/mol

Ref: 54-OR1030127

Olmesartan Medoxomil

CAS: 144689-63-4

Formula: C₂₉H₃₀N₆O₆

Color and Shape: White To Off-White Solid

Molecular weight: 558.60

Ref: 4Z-O-083

Olmesartan medoxomil, EP grade

CAS: 144689-63-4

Formula: C₂₉H₃₀N₆O₆

Molecular weight: 558.59

Ref: 7W-GP8971

Olmesartan medoxomil

CAS: 144689-63-4

Formula: C₂₉H₃₀N₆O₆

Purity: 98.0 - 102.0 % (dried basis)

Color and Shape: White to almost white powder

Molecular weight: 558.59

Ref: 7W-GP3934

Olmesartan Medoxomil

CAS: 144689-63-4

Olmesartan Medoxomil

Purity: ≥98%

Molecular weight: 558.59g/mol

Ref: 54-BUP15452

Olmesartan Medoxomil

Controlled Product

CAS: 144689-63-4

Formula: C₂₉H₃₀N₆O₆

Color and Shape: Neat

Molecular weight: 558.59

Ref: 86-MM1317.00

Olmesartan Medoxomil RS

CAS: 144689-63-4

Color and Shape: White To Pale Yellow-White Solid Crystalline Powder

Ref: 2K-1034800021

Olmesartan Medoxomil

Controlled Product

CAS: 144689-63-4

Applications An angiotensin II receptor antagonist. Used as an anti-hypertensive.
References Yanagisawa, H., et al.: J. Med. Chem., 39, 323 (1996), Puchler, K., et al.: J. Hypertens., 15, 1809 (1997),

Formula: C₂₉H₃₀N₆O₆

Color and Shape: White

Molecular weight: 558.59

Ref: TR-O550000

Olmesartan medoxomil

CAS: 144689-63-4

Olmesartan is a drug that belongs to the class of angiotensin II receptor antagonists. It is used for the treatment of high blood pressure, heart failure, and kidney disease. The therapeutic effect of olmesartan can be increased by concomitant use with other drugs if it is being used as a combination therapy. This drug interacts with many other drugs, including diuretics and ACE inhibitors. Drugs that are known to interact with olmesartan include furosemide, hydrochlorothiazide, amiloride, spironolactone, triamterene, chlorothiazide and quinethazone. Blood sampling is often required during therapy in order to monitor the efficacy of this drug.

Formula: C₂₉H₃₀N₆O₆

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 558.59 g/mol

Ref: 3D-IH57934

Olmesartan Medoxomil

CAS: 144689-63-4

Color and Shape: Neat

Ref: 61-FOR1317.00