CAS 1447-88-7

Hispidulin

Description:

Hispidulin is a naturally occurring flavonoid compound, classified under the category of flavones. It is primarily derived from various plant sources, particularly those in the Asteraceae family. The chemical structure of hispidulin features a chromone backbone, which is characteristic of flavonoids, and includes hydroxyl groups that contribute to its biological activity. This compound is known for its potential antioxidant, anti-inflammatory, and neuroprotective properties, making it of interest in pharmacological research. Additionally, hispidulin has been studied for its effects on various cellular pathways, suggesting potential therapeutic applications in conditions such as cancer and neurodegenerative diseases. Its solubility and stability can vary depending on the solvent and environmental conditions, which is important for its application in both research and potential medicinal use. Overall, hispidulin represents a significant area of study within natural products chemistry, with ongoing research aimed at elucidating its mechanisms of action and potential health benefits.

Formula: C₁₆H₁₂O₆

InChI: InChI=1/C16H12O6/c1-21-16-11(19)7-13-14(15(16)20)10(18)6-12(22-13)8-2-4-9(17)5-3-8/h2-7,17,19-20H,1H3

InChI key: InChIKey=IHFBPDAQLQOCBX-UHFFFAOYSA-N

SMILES: OC1=C2C(OC(=CC2=O)C3=CC=C(O)C=C3)=CC(O)=C1OC

Synonyms:

• 4H-1-Benzopyran-4-one, 5,7-dihydroxy-2-(4-hydroxyphenyl)-6-methoxy-
• 4′,5,7-Trihydroxy-6-methoxyflavone
• 5,7,4′-Trihydroxy-6-methoxyflavone
• 5,7-Dihydroxy-2-(4-hydroxyphenyl)-6-methoxy-4H-1-benzopyran-4-one
• 5,7-dihydroxy-2-(4-hydroxyphenyl)-6-methoxy-4H-chromen-4-one
• 6-Methoxy-5,7,4′-trihydroxyflavone
• 6-Methoxyapigenin
• 6-Methylscutellarein
• 6-O-Methylscutellarein
• Dinatin
• Flavone, 4′,5,7-trihydroxy-6-methoxy-
• Hispedulin
• Hispiludin
• NSC 122415
• Salvitin
• Scutellarein 6-Methyl Ether
• Hispidulin
• Hispidulin, >99%
• 1447-88-7
• Hispidulin(Dinatin)
• 5,7-dihydroxy-2-(4-hydroxyphenyl)-6-methoxychromen-4-one
• 4',5,7-Trihydroxy-6-methoxyflavone

Hispidulin

CAS: 1447-88-7

Hispidulin analytical standard provided with w/w absolute assay, to be used for quantitative titration.

Formula: C₁₆H₁₂O₆

Purity: (HPLC) ≥95%

Color and Shape: Powder

Molecular weight: 300.27

Ref: 11-1451

4H-1-Benzopyran-4-one, 5,7-dihydroxy-2-(4-hydroxyphenyl)-6-methoxy-

CAS: 1447-88-7

Formula: C₁₆H₁₂O₆

Purity: 99%

Color and Shape: Solid

Molecular weight: 300.2629

Ref: IN-DA001K12

Hispidulin

CAS: 1447-88-7

Formula: C₁₆H₁₂O₆

Molecular weight: 300.27

Ref: 7W-GY8195

Hispidulin

CAS: 1447-88-7

Hispidulin

Purity: ≥95%

Molecular weight: 300.26g/mol

Ref: 54-BUP17580

Hispidulin

CAS: 1447-88-7

Hispidulin has anti-oxidative, anti-inflammatory, anti-cancer, antiepileptic, neuroprotective, anti-osteoporotic and bone resorption attenuating effects, it targets the VEGF receptor 2-mediated PI3K/Akt/mTOR signaling pathway in endothelial cells, leading to the suppression of pancreatic tumor growth and angiogenesis. Hispidulin can ameliorate high glucose-mediated endothelial dysfunction via inhibiting PKCβII-associated NLRP3 inflammasome activation and NF-κB signaling, it has potential application in the prevention and treatment of diabetic vascular complications. Hispidulin can inhibit platelet aggregation by elevating cAMP levels by a mechanism different from that of theophylline or PGE1.

Formula: C₁₆H₁₂O₆

Purity: 95%~99%

Molecular weight: 300.266

Ref: BP-BP0730

Hispidulin

CAS: 1447-88-7

Hispidulin, a natural flavone with a broad spectrum of biological activities, is a Pim-1 inhibitor (IC50: 2.71 μM).

Formula: C₁₆H₁₂O₆

Purity: 98.53% - 99.87%

Color and Shape: Solid

Molecular weight: 300.26

Ref: TM-TQ0201

Hispidulin

CAS: 1447-88-7

Formula: C₁₆H₁₂O₆

Molecular weight: 300.27

Ref: 4Z-H-031001

Hispidulin

CAS: 1447-88-7

Oxygen-heterocyclic compound

Formula: C₁₆H₁₂O₆

Purity: ≥ 95.0 % (HPLC)

Color and Shape: Powder

Molecular weight: 300.27

Ref: 5G-83335

Hispidulin

CAS: 1447-88-7

Hispidulin is a naturally occurring flavonoid compound, which is predominantly derived from plants such as Salvia and Artemisia species. This bioactive compound exhibits a broad spectrum of pharmacological activities that have garnered attention in the scientific community. Its mode of action involves the modulation of cellular pathways, including the inhibition of enzymes like cyclooxygenases, which are pivotal in inflammatory responses. Furthermore, Hispidulin has been shown to influence neurotransmitter systems, including GABAergic activity, indicating potential neuroprotective effects.

Formula: C₁₆H₁₂O₆

Purity: Min. 98 Area-%

Color and Shape: Off-White Powder

Molecular weight: 300.26 g/mol

Ref: 3D-FH73251

Hispidulin - Bio-X ™

CAS: 1447-88-7

This product is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready-to-use products for assay development, screening or other R&D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use.

Formula: C₁₆H₁₂O₆

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 300.26 g/mol

Ref: 3D-BH300089

Hispidulin

CAS: 1447-88-7

Purity: 99%

Molecular weight: 300.2659912

Ref: 10-F814360

Hispidulin

Controlled Product

CAS: 1447-88-7

Applications Hispidulin is a potent benzodiazepine (BZD) receptor ligand.

Formula: C₁₆H₁₂O₆

Color and Shape: Neat

Molecular weight: 300.27

Ref: TR-H456340

Hispidulin

CAS: 1447-88-7

Hispidulin analytical standard provided with w/w absolute assay, to be used for quantitative titration.

Formula: C₁₆H₁₂O₆

Purity: (HPLC) ≥98%

Color and Shape: Powder

Molecular weight: 300.27

Ref: 11-1451S