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CAS 144701-24-6

:

fmoc-D-norvaline

Description:
Fmoc-D-norvaline is a derivative of the amino acid norvaline, modified with a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is commonly used in peptide synthesis. The Fmoc group serves to protect the amino group during the coupling reactions, allowing for selective reactions at the carboxyl group. This compound is characterized by its white to off-white crystalline solid form and is soluble in organic solvents such as dimethyl sulfoxide (DMSO) and dimethylformamide (DMF), but generally insoluble in water. Fmoc-D-norvaline is utilized in the synthesis of peptides and proteins, particularly in the context of solid-phase peptide synthesis (SPPS). Its structure includes a chiral center, making it an important building block for the synthesis of peptides with specific stereochemistry. Additionally, the presence of the Fmoc group allows for easy removal under basic conditions, facilitating the progression of peptide synthesis. As with many chemical substances, proper handling and storage are essential to maintain its stability and efficacy in laboratory settings.
Formula:C20H21NO4
Synonyms:
  • Fmoc-D-Nva-OH
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