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CAS 144701-48-4

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Telmisartan

Description:
Telmisartan is an angiotensin II receptor antagonist primarily used in the treatment of hypertension and to reduce cardiovascular risk. It is characterized by its ability to selectively block the AT1 receptor, which plays a crucial role in regulating blood pressure and fluid balance. Telmisartan is a white to off-white crystalline powder that is practically insoluble in water but soluble in organic solvents like ethanol and methanol. Its molecular formula is C33H30N4O2, and it has a relatively high molecular weight. The substance exhibits a long half-life, allowing for once-daily dosing, which enhances patient compliance. Telmisartan also possesses additional properties, such as potential benefits in metabolic syndrome and protective effects on renal function. It is important to note that, like other medications, telmisartan may have side effects, including dizziness, fatigue, and gastrointestinal disturbances. Overall, telmisartan is a well-established medication in the management of hypertension, with a favorable safety profile and efficacy in cardiovascular risk reduction.
Formula:C16H18N4O3S
InChI:InChI=1/C33H30N4O2/c1-7-12-33-39-34-24(2)21-27(35-38-30-15-10-11-16-31(30)40(35)6)22-32(34)41(33)23-25-17-19-26(20-18-25)28-13-8-9-14-29(28)36(42)43-37(3,4)5/h8-11,13-22H,7,12,23H2,1-6H3
InChI key:InChIKey=RMMXLENWKUUMAY-UHFFFAOYSA-N
SMILES:C(N1C=2C(N=C1CCC)=C(C)C=C(C2)C=3N(C)C=4C(N3)=CC=CC4)C5=CC=C(C=C5)C6=C(C(O)=O)C=CC=C6
Synonyms:
  • 2-(4-[[4-Methyl-6-(1-methyl-1H-1,3-benzodiazol-2-yl)-2-propyl-1H-1,3-benzodiazol-1-yl]methyl]phenyl)benzoic acid
  • 2-[4-[[4-Methyl-6-(1-Methylbenzoimidazol-2-Yl)-2-Propyl-Benzoimidazol-1-Yl]Methyl]Phenyl]Benzoic Acid
  • 2-[4-[[4-Methyl-6-(1-methylbenzimidazol-2-yl)-2-propylbenzimidazol-1-yl]methyl]phenyl]benzoic acid
  • 4'-[(1,7'-dimethyl-2'-propyl-1H,3'H-2,5'-bibenzimidazol-3'-yl)methyl]biphenyl-2-carboxylic acid
  • 4'-[[4-Methyl-6-(1-methyl-2-benzimidazolyl)-2-propyl-1-benzimidazolyl]methyl]-2-biphenylcarboxylic acid
  • 4'[(1,4'-Dimethyl-2'-propyl[2,6'-bi-1H-benzimidazol]-1'-yl)methyl][1,1'-biphenyl]-2-carboxylic acid
  • Bibr 277
  • Bibr 277Se
  • Kinzalmono
  • Micardis
  • See more synonyms
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products per page.Found 21 products.
  • Telmisartan-d4
    TRC
    + Info

    Telmisartan-d4

    Controlled Product
    CAS:

    Applications Telmisartan-d4 is deuterium labelled Telmisartan (T017000). Telmisartan is an angiotensin II receptor antagonist.
    References Wienen, W. et al.: Br. J. Pharmacol., 110, 245 (1993); Neutel, J.M. et al: Adv. Therap., 15, 206 (1998)

    Formula:C33D4H26N4O2
    Color and Shape:Neat
    Molecular weight:518.64

    Ref: TR-T017001

    1mg
    659.00€
    10mg
    4,449.00€