CAS 1448-36-8

Methyl cholate

Description:

Methyl cholate, with the CAS number 1448-36-8, is a bile acid derivative that plays a role in the digestion and absorption of fats in the body. It is a methyl ester of cholate, which is a naturally occurring bile acid. Methyl cholate is characterized by its amphipathic nature, possessing both hydrophilic and hydrophobic properties, allowing it to interact with lipids and facilitate emulsification. This compound typically appears as a white to off-white solid and is soluble in organic solvents. Its molecular structure includes a steroid backbone with hydroxyl groups, contributing to its biological activity. Methyl cholate is often studied for its potential applications in biochemistry and pharmacology, particularly in understanding lipid metabolism and the role of bile acids in various physiological processes. Additionally, it may be used in research related to drug delivery systems and the formulation of lipid-based therapies. As with many bile acids, its behavior in biological systems can be influenced by factors such as pH and the presence of other molecules.

Formula: C₂₅H₄₂O₅

InChI: InChI=1S/C25H42O5/c1-14(5-8-22(29)30-4)17-6-7-18-23-19(13-21(28)25(17,18)3)24(2)10-9-16(26)11-15(24)12-20(23)27/h14-21,23,26-28H,5-13H2,1-4H3/t14-,15+,16-,17-,18+,19+,20-,21+,23+,24+,25-/m1/s1

InChI key: InChIKey=DLYVTEULDNMQAR-SRNOMOOLSA-N

SMILES: O[C@H]1[C@]2([C@]3([C@@](C)([C@@]([C@@H](CCC(OC)=O)C)(CC3)[H])[C@@H](O)C[C@@]2([C@]4(C)[C@](C1)(C[C@H](O)CC4)[H])[H])[H])[H]

Synonyms:

• Cholan-24-oic acid, 3,7,12-trihydroxy-, methyl ester, (3α,5β,7α,12α)-
• Cholic acid methyl ester
• Methyl (3Alpha,5Beta,12Alpha)-3,7,12-Trihydroxycholan-24-Oate
• Methyl 3,7,12-Trihydroxycholan-24-Oate
• Methyl 3α,7α,12α-trihydroxy-5β-cholan-24-ate
• Methyl 3α,7α,12α-trihydroxy-5β-cholan-24-oate
• Methyl 3α,7α,12α-trihydroxy-5β-cholanoate
• Methyl 4-(3,7,12-trihydroxy-10,13-dimethylperhydrocyclopenta[a]phenanthren-17-yl)pen
• NSC 126794
• methyl (3beta,5alpha,7beta,12alpha,17alpha,20S)-3,7,12-trihydroxycholan-24-oate
• methyl 4-[(3R,5S,7R,10S,12S,13R,17R)-3,7,12-trihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoate
• methyl 4-[(3R,7R,10S,12S,13R,17R)-3,7,12-trihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoate

Methyl Cholate

CAS: 1448-36-8

Formula: C₂₅H₄₂O₅

Purity: >98.0%(GC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 422.61

Ref: 3B-C1412

Methyl cholate, 97%

CAS: 1448-36-8

Methyl cholate, is used as a bile acid derivative as anti-inflammatory and antitumor agent. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product

Formula: C₂₅H₄₂O₅

Purity: 97%

Color and Shape: White to cream, Crystals or powder or crystalline powder

Molecular weight: 422.61

Ref: 02-L05129

Cholan-24-oic acid, 3,7,12-trihydroxy-, methyl ester, (3α,5β,7α,12α)-

CAS: 1448-36-8

Formula: C₂₅H₄₂O₅

Purity: 95%

Color and Shape: Solid

Molecular weight: 422.5980

Ref: IN-DA001K6U

Methyl Cholate

CAS: 1448-36-8

Methyl Cholate (Cholic acid methyl ester) is the methyl form of cholic acid.

Formula: C₂₅H₄₂O₅

Purity: 96.22%

Color and Shape: Off-White Solid

Molecular weight: 422.6

Ref: TM-T2744

Methyl Cholate

CAS: 1448-36-8

Methyl Cholate

Purity: ≥98%

Molecular weight: 422.6g/mol

Ref: 54-BUP16528

Methyl Cholate

CAS: 1448-36-8

Formula: C25H42O5

Purity: >98%

Color and Shape: Solid

Molecular weight: 422.6

Ref: 48-65-1002

Methyl Cholate

CAS: 1448-36-8

Color and Shape: Neat

Ref: 86-MM0835.12

Methyl Cholate

CAS: 1448-36-8

Formula: C₂₅H₄₂O₅

Molecular weight: 422.61

Ref: 4Z-C-57120

METHYL CHOLATE

CAS: 1448-36-8

Purity: 95%

Color and Shape: Solid

Molecular weight: 422.605987548828

Ref: 10-F795817

Cholic Acid Methyl Ester

CAS: 1448-36-8

Formula: C₂₅H₄₂O₅

Molecular weight: 422.61

Ref: ST-EA-CP-C93014

Methyl Cholate

Controlled Product

CAS: 1448-36-8

Applications A bile acid derivative as anti-inflammatory and antitumor agent.
References Yasukawa, K., et al.: Chem. Pharm. Bull, 19, 573 (1996), Yasukawa, K., et al.: J. Pharm. Pharmacol., 52, 119 (2000), Iida, T., et al.: Lipids, 38, 281 (2003),

Formula: C₂₅H₄₂O₅

Color and Shape: Neat

Molecular weight: 422.60

Ref: TR-M294475

Cholic acid methyl ester

Controlled Product

CAS: 1448-36-8

Cholic acid methyl ester is a bile acid derivative, which is synthesized from cholic acid, a primary bile acid produced in the liver from cholesterol. This compound is obtained through the esterification process, where the carboxylic acid group of cholic acid is modified into its methyl ester form, resulting in enhanced lipophilic properties compared to its parent compound.

Formula: C₂₅H₄₂O₅

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 422.6 g/mol

Ref: 3D-FC58659

Cholic Acid Methyl Ester

Controlled Product

CAS: 1448-36-8

Applications Protected Cholic Acid
References Suzuki, T., et al.: J. Pharmacol. Sci., 107, 285 (2008), Yasukawa, K., et al.: J. Pharm. Pharmacol., 61, 1051 (2009), Aher, N., et al.: Bioorg. Med. Chem. Lett., 19, 5411 (2009), Huang, L., et al.: Steroids, 74, 701 (2009),

Formula: C₂₅H₄₂O₅

Color and Shape: Neat

Molecular weight: 422.60

Ref: TR-C432610