CAS 144809-28-9

5-[4-[2-(5-Ethyl-pyridin-2-yl-ethoxy)benzyldene]thiazolidine]-2,4-dione

Description:

5-[4-[2-(5-Ethyl-pyridin-2-yl-ethoxy)benzyldene]thiazolidine]-2,4-dione, with the CAS number 144809-28-9, is a synthetic organic compound that belongs to the class of thiazolidinediones. This compound features a thiazolidine ring, which is a five-membered heterocyclic structure containing sulfur and nitrogen, and is characterized by the presence of a dione functional group, indicating two carbonyl (C=O) groups. The ethyl-pyridine moiety suggests that it has potential biological activity, as pyridine derivatives are often associated with various pharmacological properties. The compound's structure includes an ethoxy group, which enhances its solubility and reactivity. Its unique arrangement of functional groups may contribute to its potential applications in medicinal chemistry, particularly in the development of therapeutic agents. The compound's properties, such as solubility, stability, and reactivity, would be influenced by its molecular structure, making it a subject of interest for further research in drug development and chemical synthesis.

Formula: C₁₉H₁₈N₂O₃S

InChI: InChI=1/C19H18N2O3S/c1-2-13-3-6-15(20-12-13)9-10-24-16-7-4-14(5-8-16)11-17-18(22)21-19(23)25-17/h3-8,11-12H,2,9-10H2,1H3,(H,21,22,23)/b17-11+

InChI key: InChIKey=YNTUJOCADSTMCL-UHFFFAOYSA-N

SMILES: C(=C1C(=O)NC(=O)S1)C2=CC=C(OCCC3=CC=C(CC)C=N3)C=C2

Synonyms:

• (5E)-5-({4-[2-(5-ethylpyridin-2-yl)ethoxy]phenyl}methylidene)-1,3-thiazolidine-2,4-dione
• 2,4-Thiazolidinedione, 5-[[4-[2-(5-ethyl-2-pyridinyl)ethoxy]phenyl]methylene]-
• 5-[4-[2-(5-Ethyl-2-pyridinyl)ethoxy]benzylidene]-1,3-thiazolidine-2,4-dione
• 5-[4-[2-(5-Ethyl-2-pyridinyl)ethoxy]benzylidene]-2,4-thiazolidinedione
• 5-[4-[2-(5-Ethyl-2-pyridyl)ethoxy]benzylidene]thiazolidine-2,4-dione
• 5-[4-[2-(5-Ethylpyridin-2-yl)ethoxy]benzylidene]thiazolidine-2,4-dione
• 5-[[4-[2-(5-Ethyl-2-Pyridinyl)Ethoxy]Phenyl]Methylene]-2,4-Thiazolidinone
• 5-[[4-[2-(5-Ethyl-2-Pyridinyl)ethoxy]phenyl]methylene]-2,4-thiazolidinedione
• 5-{4-[2-(5-Ethyl-2-pyridinyl)ethoxyl]benzyldene}-2,4-thiazolidinedione
• 5-{4-[2-(5-Ethyl-pyridin-2-yl)-ethoxy]-
• 5-[[4-[2-(5-ethyl-2-pyridinyl)ethoxy]
• 5-(4-(2-(5-ETHYL-2-PYRIDINYDETHOXY)BENZYLIDENE)-2,4-THIAZOL
• 5-[4-[2-(5-ETHYL-PURIDIN-2-YL-ETHOXY)BENZYLDENE]THIAZOLIDINE-2,4-DIONE

2,4-Thiazolidinedione, 5-[[4-[2-(5-ethyl-2-pyridinyl)ethoxy]phenyl]methylene]-

CAS: 144809-28-9

Formula: C₁₉H₁₈N₂O₃S

Purity: 99%

Color and Shape: Solid

Molecular weight: 354.4228

Ref: IN-DA001K73

5-(4-(2-(5-Ethylpyridin-2-Yl)Ethoxy)Benzylidene)Thiazolidine-2,4-Dione

CAS: 144809-28-9

5-(4-(2-(5-Ethylpyridin-2-Yl)Ethoxy)Benzylidene)Thiazolidine-2,4-Dione

Purity: 97%

Molecular weight: 354.42g/mol

Ref: 54-OR1027615

5-[[4-[2-(5-Ethyl-2-pyridinyl)ethoxy]phenyl]-methylene]-2,4-thiazolidinedione(Pioglitazone Impurity)

Controlled Product

CAS: 144809-28-9

Impurity Pioglitazone EP Impurity B
Applications 5-[[4-[2-(5-Ethyl-2-pyridinyl)ethoxy]phenyl]-methylene]-2,4-thiazolidinedione (Pioglitazone EP Impurity B) is a novel intermediate of Pioglitazone (P471000).
References Diaz, J., et al.: J. Biol. Chem., 272, 11350 (1997), Day, C., et al.: Diabet Med., 16, 179 (1999), Motomura, W., et al.: Cancer Res., 60, 5558 (2000), Koeffler, H., et al.: Clin. Cancer Res., 9, 1 (2003),

Formula: C₁₉H₁₈N₂O₃S

Color and Shape: Neat

Molecular weight: 354.42

Ref: TR-E925590

5-[[4-[2-(5-Ethyl-2-pyridinyl)ethoxy]phenyl]-methylene]-2,4-thiazolidinedione

CAS: 144809-28-9

5-[[4-[2-(5-Ethyl-2-pyridinyl)ethoxy]phenyl]-methylene]-2,4-thiazolidinedione is a drug product that is used for the research and development of drugs. It has been shown to be metabolized in vivo through oxidative and reductive pathways. 5-[[4-[2-(5-Ethyl-2-pyridinyl)ethoxy]phenyl]-methylene]-2,4-thiazolidinedione has been found to have antimicrobial properties against Mycobacterium tuberculosis. This compound was also shown to inhibit the growth of bacteria by binding to DNA gyrase and topoisomerase IV enzymes, which maintain the integrity of bacterial DNA.

Formula: C₁₉H₁₈N₂O₃S

Purity: Min. 95%

Molecular weight: 354.42 g/mol

Ref: 3D-IE23114

Pioglitazone Impurity 3

CAS: 144809-28-9

Formula: C₁₉H₁₈N₂O₃S

Molecular weight: 354.4

Ref: ST-EA-CP-P7030