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CAS 144822-48-0

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1-[5-O-[Bis(4-methoxyphenyl)phenylmethyl]-2-deoxy-2-fluoro-beta-D-arabinofuranosyl]-5-methyl-2,4(1H,3H)-pyrimidinedione

Description:
1-[5-O-[Bis(4-methoxyphenyl)phenylmethyl]-2-deoxy-2-fluoro-beta-D-arabinofuranosyl]-5-methyl-2,4(1H,3H)-pyrimidinedione, with CAS number 144822-48-0, is a synthetic compound that belongs to the class of nucleoside analogs. This substance features a pyrimidinedione core, which is modified with a 2-deoxy-2-fluoro-beta-D-arabinofuranosyl moiety, enhancing its potential for biological activity. The presence of the bis(4-methoxyphenyl)phenylmethyl group contributes to its lipophilicity, potentially influencing its pharmacokinetic properties. The compound is of interest in medicinal chemistry, particularly for its potential antiviral or anticancer activities, as nucleoside analogs often interfere with nucleic acid synthesis. Its structural complexity suggests that it may exhibit unique interactions with biological targets, making it a candidate for further research in drug development. However, detailed studies on its efficacy, safety, and mechanism of action are essential for understanding its potential therapeutic applications.
Formula:C31H31FN2O7
InChI:InChI=1/C31H31FN2O7/c1-19-17-34(30(37)33-28(19)36)29-26(32)27(35)25(41-29)18-40-31(20-7-5-4-6-8-20,21-9-13-23(38-2)14-10-21)22-11-15-24(39-3)16-12-22/h4-17,25-27,29,35H,18H2,1-3H3,(H,33,36,37)/t25-,26+,27-,29?/m1/s1
Synonyms:
  • 1-{5-O-[Bis-(4-methoxyphenyl)-phenylmethyl]-2-deoxy-2-fluoro--D-arabinofuranosyl}-5-methyl-2,4(1H,3H)-pyrimidinedione
  • 1-[(3S,4R,5R)-5-[[bis(4-methoxyphenyl)-phenyl-methoxy]methyl]-3-fluoro-4-hydroxy-tetrahydrofuran-2-yl]-5-methyl-pyrimidine-2,4-dione
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