CAS 1448460-32-9

17α-Hydroxymethyl-17β-methyl-18-nor-2-oxa-5α-androst-13-en-3-one

Description:

17α-Hydroxymethyl-17β-methyl-18-nor-2-oxa-5α-androst-13-en-3-one, with the CAS number 1448460-32-9, is a synthetic steroid compound that belongs to the class of androstane derivatives. This compound features a unique structural modification, including a hydroxymethyl group at the 17α position and a methyl group at the 17β position, which contribute to its biological activity. The presence of the 2-oxa moiety indicates the incorporation of an oxygen atom into the steroid framework, which can influence its pharmacological properties. Typically, compounds of this nature are studied for their potential applications in medicinal chemistry, particularly in the development of anabolic agents or hormone therapies. The specific stereochemistry and functional groups present in this compound can affect its interaction with biological targets, such as androgen receptors. As with many synthetic steroids, understanding its characteristics, including solubility, stability, and metabolic pathways, is crucial for evaluating its efficacy and safety in potential therapeutic applications.

Formula: C₁₉H₂₈O₃

Synonyms:

• Abiraterone Impurity 57
• 17a-Hydroxymethyl-17-methyl-18-nor-2-oxa-5a-androst-13-en-3-one
• 17α-Hydroxymethyl-17β-methyl-18-nor-2-oxa-5α-androst-13-en-3-one
• Cyclopenta[5,6]naphtho[1,2-c]pyran-2(1H)-one, 4,4a,4b,5,6,7,8,9,9b,10,11,11a-dodecahydro-7-(hydroxymethyl)-4a,7-dimethyl-, (4aS,4bS,7R,9bR,11aS)-
• Abiraterone Impurity 76

17α-Hydroxymethyl-17β-methyl-18-nor-2-oxa-5α-androst-13-en-3-one

Controlled Product

CAS: 1448460-32-9

Applications 17α-Hydroxymethyl-17β-methyl-18-nor-2-oxa-5α-androst-13-en-3-one is a derivative of epiandrosterone (E578000), which is a steroid hormone that is present in normal human urine as a minor constituent , it is a less active 3β-isomer of the androgen Androsterone (A635535).
References Marchand, M., et al.: Eur. J. Biochem., 184, 455 (1989), Dardonville, C., et al.: Bioorg. Med. Chem., 11, 3205 (2003), Fumarola, L., et al.: Res. Microbiol., 155, 224 (2004), Albert, M., et al.: J. Biol. Chem., 280, 28306 (2005),

Formula: C₁₉H₂₈O₃

Purity: >90%

Color and Shape: Off-White

Molecular weight: 304.42

Ref: TR-H949820

Abiraterone Impurity 30

CAS: 1448460-32-9

Formula: C₁₉H₂₈O₃

Molecular weight: 304.43

Ref: ST-EA-CP-A67106