CAS 144875-48-9
:Resiquimod
Description:
Resiquimod is a synthetic imidazoquinoline compound that acts as an immune response modifier, primarily functioning as a toll-like receptor (TLR) 7 and TLR8 agonist. It is characterized by its ability to stimulate the innate immune system, leading to the activation of various immune cells, including dendritic cells and macrophages. This activation results in the production of pro-inflammatory cytokines and enhances both the humoral and cellular immune responses. Resiquimod is often explored for its potential therapeutic applications in treating viral infections, certain cancers, and skin conditions, such as actinic keratosis and superficial basal cell carcinoma. The compound is typically administered topically, and its formulation may include various excipients to enhance skin penetration and bioavailability. Due to its immunomodulatory effects, Resiquimod has been the subject of numerous clinical studies, highlighting its role in enhancing vaccine efficacy and its potential as an adjuvant in immunotherapy. Safety profiles indicate that it may cause local skin reactions, which are generally mild and transient.
Formula:C17H22N4O2
InChI:InChI=1S/C17H22N4O2/c1-4-23-9-13-20-14-15(21(13)10-17(2,3)22)11-7-5-6-8-12(11)19-16(14)18/h5-8,22H,4,9-10H2,1-3H3,(H2,18,19)
InChI key:InChIKey=BXNMTOQRYBFHNZ-UHFFFAOYSA-N
SMILES:C(C(C)(C)O)N1C=2C=3C(N=C(N)C2N=C1COCC)=CC=CC3
Synonyms:- 1-[4-Amino-2-(ethoxymethyl)imidazo[4,5-c]quinolin-1-yl]-2-methylpropan-2-ol
- 1H-Imidazo[4,5-c]quinoline-1-ethanol, 4-amino-2-(ethoxymethyl)-α,α-dimethyl-
- 4-Amino-2-(ethoxymethyl)-1-(2-hydroxyisobutyl)imidazo[4,5-c]quinoline
- 4-Amino-2-(ethoxymethyl)-alpha,alpha-dimethyl-1H-imidazo[4,5-c]quinoline-1-ethanol
- 4-Amino-2-(ethoxymethyl)-α,α-dimethyl-1H-imidazo[4,5-c]quinoline-1-ethanol
- R-848
- Resimiquimod
- Resiquimod
- S-28463
- Vml-600
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Found 11 products.
Resiquimod
CAS:Formula:C17H22N4O2Purity:>98.0%(HPLC)Color and Shape:White to Light yellow to Light orange powder to crystalMolecular weight:314.391H-Imidazo[4,5-c]quinoline-1-ethanol, 4-amino-2-(ethoxymethyl)-α,α-dimethyl-
CAS:Formula:C17H22N4O2Purity:98%Color and Shape:SolidMolecular weight:314.38221-(4-Amino-2-(ethoxymethyl)-1H-imidazo[4,5-c]quinolin-1-yl)-2-methylpropan-2-ol
CAS:1-(4-Amino-2-(ethoxymethyl)-1H-imidazo[4,5-c]quinolin-1-yl)-2-methylpropan-2-olFormula:C17H22N4O2Purity:98%Color and Shape: off-white solidMolecular weight:314.38g/molResiquimod
CAS:<p>Resiquimod (R848) is a TLR7/TLR8 agonist. Resiquimod is an immunomodulator with antitumor and antiviral activity. Cost-effective and quality-assured.</p>Formula:C17H22N4O2Purity:99.62% - 99.95%Color and Shape:SolidMolecular weight:314.38Resiquimod
CAS:Formula:C17H22N4O2Purity:≥ 98.0%Color and Shape:Off-white solidMolecular weight:314.38Resiquimod
CAS:<p>Resiquimod activates the immune system by binding to toll-like receptor 7 (TLR-7) and TLR8, which are receptors expressed on dendritic cells, macrophages and other antigen-presenting cells. Resiquimod can also activate the immune system by activating cell factor, a protein found in white blood cells that plays an important role in the activation of T lymphocytes.</p>Formula:C17H22N4O2Purity:Min. 98 Area-%Color and Shape:White PowderMolecular weight:314.38 g/mol1-(4-Amino-2-(ethoxymethyl)-1H-imidazo[4,5-c]quinolin-1-yl)-2-methylpropan-2-ol
CAS:Formula:C17H22N4O2Purity:98%Color and Shape:Solid, PowderMolecular weight:314.389Resiquimod
CAS:<p>Applications Resiquimod is an imidazoquinoline derivative that acts as an immune response modifier. Resiquimod shows antitumor and antiviral activity and is used in the treatment of skin lesions such as herpes simplex virus. Resiquimod is a toll-like receptor 9 (TLR7) agonist.<br>References Wu, J.J. et al.: Antivir. Res., 64, 79 (2004); Fife, K.H. et al.: Antimicrob. Agents Chemother., 52, 477 (2008); Szeimies, R.M. et al.: Brit. J. Dermatol., 159, 205 (2008);<br></p>Formula:C17H22N4O2Color and Shape:White SolidMolecular weight:314.38
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