CAS 1449277-10-4

8-Amino-N-[1-(cyclopropylcarbonyl)-3-azetidinyl]-2-(3-fluorophenyl)-1,7-naphthyridine-5-carboxamide

CAS: 1449277-10-4

Formula: C₂₂H₂₀FN₅O₂

Purity: 97%

Color and Shape: Solid

Molecular weight: 405.4249

Ref: IN-DA003ATD

GNE-495

CAS: 1449277-10-4

GNE-495

Purity: ≥98%

Molecular weight: 405.42g/mol

Ref: 54-BUP16304

GNE-495

CAS: 1449277-10-4

GNE-495

Formula: C₂₂H₂₀FN₅O₂

Purity: 99.7% (Typical Value in Batch COA)

Color and Shape: yellow solid

Molecular weight: 405.42g/mol

Ref: 54-BISN0201

GNE-495

CAS: 1449277-10-4

GNE-495 is a potent and specific MAP4K4 inhibitor (IC50: 3.7 nM).

Formula: C₂₂H₂₀FN₅O₂

Purity: 99.22% - 99.57%

Color and Shape: Solid

Molecular weight: 405.42

Ref: TM-TQ0079

GNE-495

CAS: 1449277-10-4

GNE-495 is a small molecule inhibitor, which is synthetically derived through medicinal chemistry processes. Its mode of action involves targeting specific kinase pathways that are crucial for the proliferation and survival of cancer cells. By inhibiting these kinases, GNE-495 disrupts signaling pathways, leading to reduced tumor growth and potential apoptosis in malignant cells.

Formula: C₂₂H₂₀FN₅O₂

Purity: Min. 95%

Molecular weight: 405.42 g/mol

Ref: 3D-ZHC27710