CAS 145-14-2

20α-Dihydroprogesterone

Description:

20α-Dihydroprogesterone, also known as 20α-hydroxyprogesterone, is a steroid hormone that is a derivative of progesterone. It is characterized by the presence of a hydroxyl group at the 20α position, which distinguishes it from its parent compound. This substance is typically a white to off-white crystalline powder and is soluble in organic solvents such as ethanol and chloroform, but has limited solubility in water. It plays a role in various biological processes, particularly in the reproductive system, where it is involved in the regulation of the menstrual cycle and pregnancy. 20α-Dihydroprogesterone is also known for its anti-inflammatory properties and is sometimes studied for its potential therapeutic applications. Its chemical structure includes a steroid backbone, which is common among hormones, and it exhibits specific binding affinity to progesterone receptors. As with many steroid hormones, it is important to handle this compound with care, considering its biological activity and potential effects on human health.

Formula: C₂₁H₃₂O₂

InChI: InChI=1S/C21H32O2/c1-13(22)17-6-7-18-16-5-4-14-12-15(23)8-10-20(14,2)19(16)9-11-21(17,18)3/h12-13,16-19,22H,4-11H2,1-3H3/t13-,16-,17+,18-,19-,20-,21+/m0/s1

InChI key: InChIKey=RWBRUCCWZPSBFC-RXRZZTMXSA-N

SMILES: C[C@@]12[C@@]3([C@]([C@]4([C@](C)(CC3)[C@@]([C@H](C)O)(CC4)[H])[H])(CCC1=CC(=O)CC2)[H])[H]

Synonyms:

• (20R)-20-hydroxypregn-4-en-3-one
• (20S)-20-Hydroxypregn-4-en-3-on
• (20S)-20-Hydroxypregn-4-en-3-one
• (20S)-20-hidroxipregn-4-en-3-ona
• (20S)-20-hydroxypregn-4-ene-3-one
• (8S,9S,10R,13S,14S,17S)-17-(1-hydroxyethyl)-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one
• (8xi,9xi,14xi,17xi,20S)-20-hydroxypregn-4-en-3-one
• 20(S)-Hydroxyprogesterone
• 20-Hydroxypregn-4-En-3-One
• 20-alpha-Dihydroprogesterone
• 20-alpha-Hydroxydihydroprogesterone
• 20-alpha-Hydroxyprogesterone
• 20-alpha-Progerol
• 20alpha-Dihydroprogesterone
• 20alpha-Dihydroprognenolone
• 20alpha-Hydroxydihydroprogesterone
• 20alpha-Hydroxypreg-4-en-3-one
• 20alpha-Hydroxypregnen-2-one
• 20alpha-Progerol
• 20α-Dihydroprogesterone
• 20α-Hydroxy-4-pregnen-3-one
• 20α-Hydroxy-Δ4-pregnen-3-one
• 20α-Hydroxy-Δ⁴-pregnen-3-one
• 20α-Hydroxydihydroprogesterone
• 20α-Hydroxypregn-4-en-3-one
• 20α-Hydroxyprogesterone
• 20α-Progerol
• 4-Pregnen-3-one-20α-ol
• Brn 2220567
• Dihydrogesterone
• Dihydroprogesterone
• Nsc 68630
• Pregn-4-en-20α-ol-3-one
• Pregn-4-en-3-one, 20-alpha-hydroxy-
• Pregn-4-en-3-one, 20-hydroxy-, (20S)-
• Pregn-4-en-3-one, 20-hydroxy-, (20S)- (9CI)
• Pregn-4-en-3-one, 20alpha-hydroxy- (8CI)
• Pregn-4-en-3-one, 20α-hydroxy-
• Pregn-4-ene-20α-ol-3-one
• Progesterol-20-alpha
• Progesterol-20α
• Δ4-Pregnen-20α-ol-3-one
• Δ4-Pregnene-20α-ol-3-one
• Δ⁴-Pregnen-20α-ol-3-one
• Δ⁴-Pregnene-20α-ol-3-one

Δ4-Pregnen-20α-ol-3-one

CAS: 145-14-2

Formula: C₂₁H₃₂O₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 316.4776

Ref: IN-DA001KFR

Progesterone EP Impurity B (20(S)-Hydroxy Progesterone)

CAS: 145-14-2

Formula: C₂₁H₃₂O₂

Color and Shape: White To Off-White Solid

Molecular weight: 316.49

Ref: 4Z-P-3223

20α-Dihydroprogesterone

CAS: 145-14-2

20α-Dihydroprogesterone

Purity: 98%

Ref: 54-OR1037183

δ4-Pregnen-20α-ol-3-one

Controlled Product

CAS: 145-14-2

Impurity Progesterone EP Impurity B
Applications Δ4-Pregnen-20α-ol-3-one (Progesterone EP Impurity B) is the main metabolite of Progesterone (P755900). Studies shows regulation of estrogen receptor levels in breast cancer by Δ4-Pregnen-20α-ol-3-one and other progesterone metabolites.
References Zhang, L. et al.: Yaoz. Xueb., 39, 613 (2004); Pawlak, K.J. et al.: J. Steroid. Biochem. Mol. Biol., 107, 172 (2007);

Formula: C₂₁H₃₂O₂

Color and Shape: Off White Solid

Molecular weight: 316.48

Ref: TR-P712215

δ4-Pregnen-20α-ol-3-one-(d4 major)

Controlled Product

CAS: 145-14-2

Applications Labelled Δ4-Pregnen-20α-ol-3-one (P712215). Δ4-Pregnen-20α-ol-3-one is the main metabolite of Progesterone (P755900). Studies shows regulation of estrogen receptor levels in breast cancer by Δ4-Pregnen-20α-ol-3-one and other progesterone metabolites.
References Zhang, L. et al.: Yaoz. Xueb., 39, 613 (2004); Pawlak, K.J. et al.: J. Steroid. Biochem. Mol. Biol., 107, 172 (2007);

Formula: C₂₁H₂₈D₄O₂

Color and Shape: Neat

Molecular weight: 320.5

Ref: TR-P712217

4-Pregnen-20-alpha-ol-3-one

Controlled Product

CAS: 145-14-2

Progesterone is a hormone that regulates the menstrual cycle and plays a key role in pregnancy. It is produced by the corpus luteum, the placenta, and the ovaries. Progesterone is also involved in regulating other functions such as cell growth, fat metabolism, blood clotting, and water balance. The level of progesterone in urine has been shown to be a good indicator of follicular growth during ovulation. In women with metabolic disorders or lactogenic hormone deficiencies, low levels of progesterone can lead to infertility.

Formula: C₂₁H₃₂O₂

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 316.48 g/mol

Ref: 3D-FP29553

Progesterone EP Impurity B

CAS: 145-14-2

Formula: C₂₁H₃₂O₂

Molecular weight: 316.48

Ref: ST-EA-CP-P133002