CAS 145-15-3

20β-Hydroxyprogesterone

Description:

20β-Hydroxyprogesterone is a steroid hormone and a derivative of progesterone, characterized by its hydroxyl group at the 20β position. It is a white to off-white crystalline powder that is soluble in organic solvents like ethanol and methanol but has limited solubility in water. This compound plays a significant role in various biological processes, particularly in the reproductive system, where it is involved in the regulation of the menstrual cycle and pregnancy. It exhibits progestational activity, influencing the endometrial lining and supporting gestation. The chemical structure of 20β-Hydroxyprogesterone includes a steroid nucleus, which is typical of steroid hormones, and its molecular formula reflects its classification as a C21 steroid. Due to its hormonal properties, it is of interest in both clinical and research settings, particularly in studies related to reproductive health and hormone replacement therapies. Safety and handling precautions are essential when working with this compound, as with many steroid hormones, due to potential biological effects.

Formula: C₂₁H₃₂O₂

InChI: InChI=1S/C21H32O2/c1-13(22)17-6-7-18-16-5-4-14-12-15(23)8-10-20(14,2)19(16)9-11-21(17,18)3/h12-13,16-19,22H,4-11H2,1-3H3/t13-,16+,17-,18+,19+,20+,21-/m1/s1

InChI key: InChIKey=RWBRUCCWZPSBFC-SJOKZOANSA-N

SMILES: C[C@@]12[C@@]3([C@]([C@]4([C@](C)(CC3)[C@@]([C@@H](C)O)(CC4)[H])[H])(CCC1=CC(=O)CC2)[H])[H]

Synonyms:

• (20R)-20-Hydroxypregn-4-en-3-one
• 20-beta-Dihydroprogesterone
• 20-beta-Hydroxydihydroprogesterone
• 20-beta-Hydroxypregn-4-en-3-one
• 20-beta-Hydroxyprogesterone
• 20-beta-Progerol
• 20beta-Hydroxy-pregn-4-en-3-one
• 20β-Dihydroprogesterone
• 20β-Hydroxy-Δ⁴-pregnen-3-one
• 20β-Hydroxypregn-4-en-3-one
• 20β-Hydroxyprogesterone
• 20β-Progerol
• 4-Pregnen-2-beta-ol-3-one
• 4-Pregnene-20β-ol-3-one
• Pregn-4-en-20β-ol-3-one
• Pregn-4-en-3-one, 20-beta-hydroxy-
• Pregn-4-en-3-one, 20-hydroxy-, (20-R)- (9CI)
• Pregn-4-en-3-one, 20-hydroxy-, (20R)-
• Pregn-4-en-3-one, 20β-hydroxy-
• Pregn-4-ene-20β-hydroxy-3-one
• Progesterol-20-beta
• Progesterol-20β
• Δ4-Pregnene-20β-ol-3-one
• Δ⁴-Pregnen-20β-ol-3-one

Pregn-4-en-3-one, 20-hydroxy-, (20R)-

CAS: 145-15-3

Formula: C₂₁H₃₂O₂

Purity: 98.0%

Color and Shape: Solid

Molecular weight: 316.4776

Ref: IN-DA001KFQ

Progesterone EP Impurity C (20(R)-Hydroxy Progesterone)

CAS: 145-15-3

Formula: C₂₁H₃₂O₂

Color and Shape: White To Off-White Solid

Molecular weight: 316.49

Ref: 4Z-P-3224

(20R)-20-Hydroxypregn-4-en-3-one

Controlled Product

CAS: 145-15-3

Formula: C₂₁H₃₂O₂

Color and Shape: Neat

Molecular weight: 316.48

Ref: 86-MM0222.03

20b-Dihydroprogesterone

Controlled Product

CAS: 145-15-3

Impurity Progesterone EP Impurity C
Applications 20β-Dihydroprogesterone (Progesterone EP Impurity C) is an impurity of Progesterone (P755900), a steroid hormone secreted by the corpus luteum. Progesterone have various significant physiological roles, such as inducing the maturation and secretory activities of the uterine endothelium and the suppression of ovulation. Progesterone is also implicated in the etiology of breast cancer.
References Anderson, E., et al.: Breast Cancer Res., 4, 197 (2002), Lanari, C., et al.: Breast Cancer Res., 4, 240 (2002), Albrecht, E.D., et al.: Front. Biosci., 8, 416 (2003), Qiu, M., et al.: J. Steroid Biochem. Mol. Biol., 85, 147 (2003),

Formula: C₂₁H₃₂O₂

Color and Shape: White To Off-White

Molecular weight: 316.48

Ref: TR-D449750

4-Pregnen-20β-ol-3-one

Controlled Product

CAS: 145-15-3

4-Pregnen-20beta-ol-3-one is a synthetic progestin that has been shown to have both contraceptive and noncontraceptive activities. It is used primarily to treat female infertility, endometriosis, and amenorrhea. The drug also has a number of other effects on the body, including anti-inflammatory and anti-angiogenic properties. 4-Pregnen-20beta-ol-3-one binds to the human liver receptor, which is responsible for its metabolism. The drug also has some activity in the endometrium of pregnant women and in the ovary cells of postmenopausal women. It increases epidermal growth factor production in skin cells and may be involved in lipid metabolism. 4-Pregnen-20beta-ol-3-one also stimulates lactogenic hormone production in women.

Formula: C₂₁H₃₂O₂

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 316.48 g/mol

Ref: 3D-FP65736

Progesterone EP Impurity C

CAS: 145-15-3

Formula: C₂₁H₃₂O₂

Molecular weight: 316.48

Ref: ST-EA-CP-P133003

Progesterone Related Compound C

CAS: 145-15-3

Ketone-alcohols and ketone-aldehydes, nesoi

Formula: C₂₁H₃₂O₂

Molecular weight: 316.24023

Ref: 45-1568010