CAS 1450-74-4

5′-Chloro-2′-hydroxyacetophenone

Description:

5′-Chloro-2′-hydroxyacetophenone, with the CAS number 1450-74-4, is an organic compound characterized by its aromatic structure, which includes a chloro substituent and a hydroxy group on the acetophenone framework. This compound typically appears as a solid and is known for its potential applications in various fields, including pharmaceuticals and organic synthesis. The presence of the chloro group enhances its reactivity, making it useful in electrophilic substitution reactions. The hydroxy group contributes to its solubility in polar solvents and can participate in hydrogen bonding, influencing its physical properties. Additionally, 5′-Chloro-2′-hydroxyacetophenone may exhibit biological activity, which can be explored for potential therapeutic uses. Its synthesis often involves standard organic reactions, and it is important to handle this compound with care due to its chemical properties. Overall, this compound serves as a valuable intermediate in the synthesis of more complex molecules in chemical research and development.

Formula: C₈H₇ClO₂

InChI: InChI=1S/C8H7ClO2/c1-5(10)7-4-6(9)2-3-8(7)11/h2-4,11H,1H3

InChI key: InChIKey=XTGCUDZCCIRWHL-UHFFFAOYSA-N

SMILES: C(C)(=O)C1=C(O)C=CC(Cl)=C1

Synonyms:

• 1-(5-Chloro-2-Hydroxyphenyl)Ethanone
• 1-(5-Chloro-2-hydroxyphenyl)ethan-1-one
• 2-Acetyl-4-chlorophenol
• 3-Chloro-6-hydroxyacetophenone
• 5-Chloro-2-hydroxyacetophenone
• Acetophenone, 5′-chloro-2′-hydroxy-
• Ethanone, 1-(5-chloro-2-hydroxyphenyl)-
• NSC 46622

Ethanone, 1-​(5-​chloro-​2-​hydroxyphenyl)​-

CAS: 1450-74-4

Formula: C₈H₇ClO₂

Purity: 95%

Color and Shape: Solid

Molecular weight: 170.5930

Ref: IN-DA001KGB

5'-Chloro-2'-hydroxyacetophenone

CAS: 1450-74-4

5'-Chloro-2'-hydroxyacetophenone

Purity: 98%

Molecular weight: 170.59g/mol

Ref: 54-OR1115

5′-Chloro-2′-hydroxyacetophenone

CAS: 1450-74-4

Formula: C₈H₇ClO₂

Purity: 95%

Color and Shape: Crystalline

Molecular weight: 170.59

Ref: 10-F012069

1-(5-Chloro-2-hydoxyphenyl)ethanone

CAS: 1450-74-4

1-(5-Chloro-2-hydoxyphenyl)ethanone is a potent inhibitor of the antiapoptotic protein survivin. It binds to the carbonyl group of the molecule, which is located on the intramolecular hydrogen bond surface. This leads to conformational changes in the molecule and ternary complex formation, which eventually leads to apoptosis protein aggregation and activation. 1-(5-Chloro-2-hydoxyphenyl)ethanone has been shown to inhibit prostate cancer cells and has also been studied in clinical trials for its anticancer properties.

Formula: C₈H₇ClO₂

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 170.59 g/mol

Ref: 3D-FC30985