CAS 145037-81-6

RHOD-2, AM

Description:

RHOD-2, AM is a cell-permeable fluorescent dye commonly used as a calcium indicator in biological research. It is a derivative of rhodamine and is designed to detect changes in intracellular calcium levels, which are crucial for various cellular processes. The "AM" designation indicates that it is an acetoxymethyl ester, allowing it to easily penetrate cell membranes. Once inside the cell, esterases hydrolyze the AM group, converting it into a more polar form that cannot easily exit the cell, thus trapping the dye inside. RHOD-2 exhibits a strong fluorescence upon binding to calcium ions, making it useful for real-time imaging of calcium dynamics in live cells. Its spectral properties allow for compatibility with various fluorescence microscopy techniques. Additionally, it is important to handle RHOD-2, AM with care, as with all chemical substances, ensuring proper storage and disposal according to safety guidelines. Overall, RHOD-2, AM is a valuable tool in cell biology for studying calcium signaling pathways.

Formula: C₅₂H₅₉BrN₄O₁₉

Synonyms:

• Xanthylium
• Xanthylium Rhod 2
• Rhizomadibotryisextract Ky-25

Rhod-2 AM

CAS: 145037-81-6

Rhod-2 AM is a fluorescent probe of the mitochondrion with λex of 552 nm and λem of 581 nm.

Formula: C₅₂H₅₉BrN₄O₁₉

Purity: 98%

Color and Shape: Solid

Molecular weight: 1123.94

Ref: TM-T19052

Rhod 2-AM

CAS: 145037-81-6

Ref: 7W-GW4199

9-[4-[Bis[2-[(acetyloxy)methoxy]-2-oxoethyl]amino]-3-[2-[2-[bis[2-[(acetyloxy)methoxy]-2-oxoethyl]amino]-5-methylphenoxy]ethoxy]phenyl]-3,6-bis(dimethylamino)xanthylium Bromide

Controlled Product

CAS: 145037-81-6

Applications 9-[4-[Bis[2-[(acetyloxy)methoxy]-2-oxoethyl]amino]-3-[2-[2-[bis[2-[(acetyloxy)methoxy]-2-oxoethyl]amino]-5-methylphenoxy]ethoxy]phenyl]-3,6-bis(dimethylamino)xanthylium Bromide is an intracellular calcium fluorescent probe.
References Valant, P.A., et. al.: J. Membrane Biol., 130, 63 (1992); Wright, K.M., et. al.: J. Exp. Botany, 47, 1779 (1996)

Formula: C₅₂H₅₉N₄O₁₉·Br

Color and Shape: Neat

Molecular weight: 1123.944

Ref: TR-B400580

9-[4-[Bis[2-[(acetyloxy)methoxy]-2-oxoethyl]amino]-3-[2-[2-[bis[2-[(acetyloxy)methoxy]-2-oxoethyl]amino]-5-methylphenoxy]ethoxy]phenyl]-3,6-bis(dimethylamino)-d12-xanthylium Bromide

Controlled Product

CAS: 145037-81-6

Applications 9-[4-[Bis[2-[(acetyloxy)methoxy]-2-oxoethyl]amino]-3-[2-[2-[bis[2-[(acetyloxy)methoxy]-2-oxoethyl]amino]-5-methylphenoxy]ethoxy]phenyl]-3,6-bis(dimethylamino)-d12-xanthylium Bromide is the labeled analogue of 9-[4-[Bis[2-[(acetyloxy)methoxy]-2-oxoethyl]amino]-3-[2-[2-[bis[2-[(acetyloxy)methoxy]-2-oxoethyl]amino]-5-methylphenoxy]ethoxy]phenyl]-3,6-bis(dimethylamino)xanthylium Bromide (B400580), an intracellular calcium fluorescent probe.
References Valant, P.A., et. al.: J. Membrane Biol., 130, 63 (1992); Wright, K.M., et. al.: J. Exp. Botany, 47, 1779 (1996)

Formula: C₅₂D₁₂H₄₇N₄O₁₉·Br

Color and Shape: Neat

Molecular weight: 1136.018

Ref: TR-B400582