![L-Glutamic acid, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-, 1-methyl ester](https://static.cymitquimica.com/cas-image/thumb-webp/25354-l-glutamic-acid-n-9h-fluoren-9-ylmethoxy-carbonyl-1-methyl-ester.webp)
CAS 145038-49-9
:L-Glutamic acid, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-, 1-methyl ester
Description:
L-Glutamic acid, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-, 1-methyl ester, commonly referred to as Fmoc-L-glutamic acid methyl ester, is a derivative of the amino acid L-glutamic acid. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is widely used in peptide synthesis to protect the amino group during the coupling reactions. The methyl ester form enhances its lipophilicity, facilitating its incorporation into various biochemical applications. The presence of the Fmoc group allows for selective deprotection under mild basic conditions, making it suitable for solid-phase peptide synthesis. This compound is typically a white to off-white solid and is soluble in organic solvents such as dichloromethane and dimethylformamide, but less soluble in water. Its molecular structure includes a carboxylic acid functional group, an amine, and an ester, contributing to its reactivity and utility in synthetic organic chemistry. Overall, Fmoc-L-glutamic acid methyl ester is an important intermediate in the synthesis of peptides and other bioactive molecules.
Formula:C21H21NO6
InChI:InChI=1S/C21H21NO6/c1-27-20(25)18(10-11-19(23)24)22-21(26)28-12-17-15-8-4-2-6-13(15)14-7-3-5-9-16(14)17/h2-9,17-18H,10-12H2,1H3,(H,22,26)(H,23,24)/t18-/m0/s1
InChI key:GVVDKFNHFXLOQY-SFHVURJKSA-N
SMILES:COC(=O)[C@H](CCC(=O)O)NC(=O)OCC1C2=CC=CC=C2C3=CC=CC=C13
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Fmoc-Glu-OMe
CAS:Fmoc-Glu-OMe is a small molecule that is synthesized by N-Fmoc chemistry. It has been shown to have synergistic effects with nitrate and antimicrobial agents, such as chloramphenicol, in the inhibition of bacterial growth. Fmoc-Glu-OMe also has strong antibacterial activity against Gram-positive bacteria such as Staphylococcus aureus and Streptococcus pyogenes. In addition, this compound is soluble in water and can be used for the delivery of hydrophobic drugs. This compound may be prepared using natural products or other chemical reactions.Formula:C21H21NO6Purity:Min. 95%Color and Shape:PowderMolecular weight:383.39 g/mol(S)-4-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-5-methoxy-5-oxopentanoic acid
CAS:Formula:C21H21NO6Purity:95%Color and Shape:SolidMolecular weight:383.4
