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CAS 145038-52-4

:

Fmoc-L-Aspartic acid 4-methyl ester

Description:
Fmoc-L-Aspartic acid 4-methyl ester is a derivative of aspartic acid, characterized by the presence of a 9-fluorenylmethoxycarbonyl (Fmoc) protecting group on the amino group and a methyl ester at the carboxylic acid position. This compound is commonly used in peptide synthesis as a building block due to its stability and ease of handling. The Fmoc group allows for selective deprotection under mild basic conditions, facilitating the stepwise assembly of peptides. The methyl ester enhances the lipophilicity of the molecule, which can influence its solubility and reactivity in various chemical environments. Fmoc-L-Aspartic acid 4-methyl ester is typically white to off-white in appearance and is soluble in organic solvents like dichloromethane and dimethylformamide. Its molecular structure includes both an amino group and a carboxyl group, making it an important component in the synthesis of peptides that require aspartic acid residues. As with many chemical substances, proper handling and storage conditions are essential to maintain its integrity and reactivity.
Formula:C20H19NO6
InChI:InChI=1/C20H19NO6/c1-26-18(22)10-17(19(23)24)21-20(25)27-11-16-14-8-4-2-6-12(14)13-7-3-5-9-15(13)16/h2-9,16-17H,10-11H2,1H3,(H,21,25)(H,23,24)/t17-/m0/s1
SMILES:COC(=O)C[C@@H](C(=O)O)N=C(O)OCC1c2ccccc2c2ccccc12
Synonyms:
  • Fmoc-Asp(Ome)-Oh
  • N-(9-Fluorenylmethyloxycarbonyl)-L-Aspartic acid 4-methyl ester
  • N-α-Fmoc-L-aspartic acid β-methyl ester
  • Fmoc-Asp-Ome
  • Fmoc-L-Asp-Ome
  • N-Alpha-(9-Fluorenylmethyloxycarbonyl)-L-Aspartic Acid Alpha-Methyl Ester
  • Fmoc-L-Aspartic acid methyl ester
  • N-Alpha-(9-Fluoroenylmethyloxycarbonyl)-L-Aspartic Acid Alpha-Methyl Ester
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