CAS 145038-53-5

Fmoc-L-Aspartic acid 4-methyl ester

Description:

Fmoc-L-Aspartic acid 4-methyl ester is a derivative of aspartic acid, an amino acid that plays a crucial role in protein synthesis. This compound features a 9-fluorenylmethoxycarbonyl (Fmoc) protective group, which is commonly used in peptide synthesis to protect the amino group during the coupling process. The presence of the methyl ester group enhances the lipophilicity of the molecule, facilitating its incorporation into various biochemical applications. Fmoc-L-Aspartic acid 4-methyl ester is typically utilized in solid-phase peptide synthesis, where it serves as a building block for the formation of peptides and proteins. Its structure allows for selective deprotection under mild conditions, making it a valuable tool in synthetic organic chemistry. The compound is generally characterized by its stability under standard laboratory conditions, although it should be handled with care due to the potential reactivity of the Fmoc group. Overall, this substance is significant in the field of biochemistry and pharmaceutical development, particularly in the synthesis of peptide-based therapeutics.

Formula: C₂₀H₁₉NO₆

InChI: InChI=1/C20H19NO6/c1-26-18(22)10-17(19(23)24)21-20(25)27-11-16-14-8-4-2-6-12(14)13-7-3-5-9-15(13)16/h2-9,16-17H,10-11H2,1H3,(H,21,25)(H,23,24)/t17-/m0/s1

InChI key: InChIKey=HSOKCYGOTGVDHL-KRWDZBQOSA-N

SMILES: C(OC(N[C@@H](CC(OC)=O)C(O)=O)=O)C1C=2C(C=3C1=CC=CC3)=CC=CC2

Synonyms:

• (2S)-2-([[(9H-Fluoren-9-yl)methoxy]carbonyl]amino)-4-methoxy-4-oxobutanoic acid
• (2S)-2-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-4-methoxy-4-oxobutanoic acid
• (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino]-4-methoxy-4-oxobutanoic acid
• 4-Methyl hydrogen N-[(9H-fluoren-9-ylmethoxy)carbonyl]-<span class="text-smallcaps">L</span>-aspartate
• <span class="text-smallcaps">L</span>-Aspartic acid, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-, 4-methyl ester
• Fmoc-Asp(Ome)-Oh
• Fmoc-Asp-Ome
• Fmoc-L-Asp-Ome
• Fmoc-L-Aspartic acid methyl ester
• N-(9-Fluorenylmethyloxycarbonyl)-L-Aspartic acid 4-methyl ester
• N-9-Fluorenylmethoxycarbonylaspartic acid β-methyl ester
• N-Alpha-(9-Fluorenylmethyloxycarbonyl)-L-Aspartic Acid Alpha-Methyl Ester
• N-Alpha-(9-Fluoroenylmethyloxycarbonyl)-L-Aspartic Acid Alpha-Methyl Ester
• N-α-Fmoc-L-aspartic acid β-methyl ester
• 4-Methyl hydrogen N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-aspartate
• L-Aspartic acid, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-, 4-methyl ester
• Fmoc-L-Asp(OMe)-OH
• Fmoc-L-7-AzaTrp-OH
• N-FMoc-L-aspartic acid 4-Methyl ester, 97%
• (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-4-methoxy-4-oxobutanoicaci
• N-Fmoc-L-asparticacid4-methylester,97%
• 2-[[9H-fluoren-9-ylmethoxy(oxo)methyl]amino]-4-methoxy-4-oxobutanoic acid
• (9H-Fluoren-9-yl)MethOxy]Carbonyl Asp(OMe)-OH
• FMoc-Aspartic acid 4-Methyl ester
• Fmoc-L-Aspartic acid 4-methyl ester USP/EP/BP
• Fmoc-L-Aspartic acid 4-methyl ester

N-Fmoc-L-aspartic acid 4-methyl ester, 97%

CAS: 145038-53-5

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₂₀H₁₉NO₆

Purity: 97%

Color and Shape: White to pale cream, Powder or crystalline powder or solid

Molecular weight: 369.37

Ref: 02-H63774

Fmoc-Asp(OMe)-OH

CAS: 145038-53-5

Bachem ID: 4046252.

Formula: C₂₀H₁₉NO₆

Purity: 100.0%

Color and Shape: White Powder

Molecular weight: 369.37

Ref: 01-4046252

L-Aspartic acid, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-, 4-methyl ester

CAS: 145038-53-5

Formula: C₂₀H₁₉NO₆

Purity: 98%

Color and Shape: Solid

Molecular weight: 369.3680

Ref: IN-DA001KHY

Fmoc-L-Asp(OMe)-OH

CAS: 145038-53-5

Formula: C₂₀H₁₉NO₆

Purity: ≥ 98.0%

Color and Shape: White powder

Molecular weight: 369.37

Ref: 7W-GM2439

N-9-Fluorenylmethoxycarbonylaspartic acid β-methyl ester

CAS: 145038-53-5

N-9-Fluorenylmethoxycarbonylaspartic acid β-methyl ester

Purity: 98%

Molecular weight: 369.37g/mol

Ref: 54-OR1032139

Fmoc-Asp(OMe)-OH

CAS: 145038-53-5

M06212 - Fmoc-Asp(OMe)-OH

Formula: C₂₀H₁₉NO₆

Purity: 95%

Color and Shape: Solid

Molecular weight: 369.373

Ref: 10-M06212

Fmoc-Asp(OMe)-OH

Controlled Product

CAS: 145038-53-5

Applications Fmoc-Asp(OMe)-OH is a useful research intermediate used in the solid phase synthesis of peptides as selective caspase-3 peptide inhibitors.
References Grimm, Erich L., et al.: Bioorg. Med. Chem., 12, 845 (2004); Vickers, C. J., et al.: J. Am. Chem. Soc., 135, 12869 (2013)

Formula: C₂₀H₁₉NO₆

Color and Shape: Neat

Molecular weight: 369.37

Ref: TR-F604205