CAS 1450833-55-2

Sulfamic acid, [(1R,2R,3S,4R)-2,3-dihydroxy-4-[[2-[3-[(trifluoromethyl)thio]phenyl]pyrazolo[1,5-a]pyrimidin-7-yl]amino]cyclopentyl]methyl ester

CAS: 1450833-55-2

Formula: C₁₉H₂₀F₃N₅O₅S₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 519.5178

Ref: IN-DA001KJ8

TAK-243

CAS: 1450833-55-2

TAK-243

Purity: ≥98%

Molecular weight: 519.52g/mol

Ref: 54-BUP12829

TAK-243

CAS: 1450833-55-2

TAK-243 (MLN7243) is a selective inhibitor of the ubiquitin-activating enzyme UAE (IC50=1 nM).

Formula: C₁₉H₂₀F₃N₅O₅S₂

Purity: 98.09% - 98.93%

Color and Shape: Solid

Molecular weight: 519.52

Ref: TM-T16974

TAK 243

CAS: 1450833-55-2

A potent inhibitor of ubiquitin activating enzyme E1. Lowers ubiquitin conjugates in cells, thereby disrupting cell signalling, cell cycle progression and repair of DNA damage. Anti-tumor effects have been demonstrated in vitro and in vivo. TAK 243 has been used to study the biology of ubiquitins and its potential as anti-cancer therapy.

Formula: C₁₉H₂₀F₃N₅O₅S₂

Purity: Min. 95%

Color and Shape: White Off-White Powder

Molecular weight: 519.52 g/mol

Ref: 3D-BT165712