CAS 1450881-55-6

SAR-20347

Description:

SAR-20347, identified by its CAS number 1450881-55-6, is a chemical compound that belongs to a class of substances typically studied for their potential therapeutic applications. While specific characteristics such as molecular weight, structure, and solubility may vary, compounds in this category often exhibit properties that make them suitable for biological activity, including interactions with specific biological targets. SAR-20347 may possess unique pharmacological properties, which could include effects on enzyme activity or receptor modulation. The compound's stability, reactivity, and safety profile are also critical factors in its evaluation for research or medicinal use. As with many chemical substances, detailed characterization would typically involve spectroscopic analysis, chromatographic techniques, and biological assays to ascertain its efficacy and safety. For precise information regarding its characteristics, including synthesis, mechanism of action, and potential applications, consulting scientific literature or databases would be essential.

Formula: C₂₁H₁₈ClFN₄O₄

Synonyms:

• CS-2527
• 4-Oxazolecarboxamide, 2-(2-chloro-6-fluorophenyl)-5-[[4-(4-morpholinylcarbonyl)phenyl]amino]-
• 2-(2-chloro-6-fluorophenyl)-5-({4-[(morpholin-4-yl)carbonyl]phenyl}amino)-1,3-oxazole-4-carboxylic acid amide
• SAR-20347
• SAR-20347;SAR 20347;SAR20347
• 2-(2-chloro-6-fluorophenyl)-5-((4-(morpholine-4-carbonyl)phenyl)amino)oxazole-4-carboxamide
• CPDD1211

4-Oxazolecarboxamide, 2-(2-chloro-6-fluorophenyl)-5-[[4-(4-morpholinylcarbonyl)phenyl]amino]-

CAS: 1450881-55-6

Formula: C₂₁H₁₈ClFN₄O₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 444.8434

Ref: IN-DA001KJ6

SAR-20347

CAS: 1450881-55-6

SAR-20347

Purity: ≥98%

Molecular weight: 444.84g/mol

Ref: 54-BUP15286

2-(2-Chloro-6-Fluorophenyl)-5-((4-(Morpholine-4-Carbonyl)Phenyl)Amino)Oxazole-4-Carboxamide

CAS: 1450881-55-6

2-(2-Chloro-6-Fluorophenyl)-5-((4-(Morpholine-4-Carbonyl)Phenyl)Amino)Oxazole-4-Carboxamide

Purity: 98%

Molecular weight: 444.84g/mol

Ref: 54-PC108411

SAR-20347

CAS: 1450881-55-6

SAR-20347 is an inhibitor of TYK2, JAK1/2/3 (IC50: 0.6/23/26/41 nM).

Formula: C₂₁H₁₈ClFN₄O₄

Purity: 98.99% - 99.77%

Color and Shape: Solid

Molecular weight: 444.84

Ref: TM-T4210

SAR-20347

CAS: 1450881-55-6

Purity: 98%

Molecular weight: 444.1

Ref: 10-F865685

SAR-20347

Controlled Product

CAS: 1450881-55-6

Formula: C₂₁H₁₈ClFN₄O₄

Color and Shape: Neat

Molecular weight: 444.84

Ref: TR-S139540

SAR-20347

CAS: 1450881-55-6

SAR-20347 is a small molecule that regulates the microenvironment of autoimmune diseases, such as multiple sclerosis and rheumatoid arthritis. It inhibits PD-L1, an immune checkpoint receptor expressed on T cells and regulatory T cells. SAR-20347 is orally administered to immunocompetent mice and reduces the number of CD4+ T cells in lymph nodes, spleen, and peripheral blood. In addition, it inhibits tumor growth by infiltration of infiltrating immune cells into the tumor tissue. This agent also has anti-tumor activity in animal models of cancer without affecting healthy tissues.

Formula: C₂₁H₁₈ClFN₄O₄

Purity: Min. 95%

Molecular weight: 444.84 g/mol

Ref: 3D-AIC88155