Glutathione peroxidase 1 (GPx1) is an important antioxidant enzyme that plays a crucial role in protecting cells from oxidative damage. It catalyzes the reduction of hydrogen peroxide and organic peroxides, utilizing glutathione as a substrate, which is a tripeptide composed of glutamate, cysteine, and glycine. GPx1 is primarily found in the cytoplasm of cells and is vital for maintaining cellular redox balance. The enzyme is characterized by its selenium-containing active site, which is essential for its catalytic activity. GPx1 is involved in various physiological processes, including detoxification of reactive oxygen species, regulation of cellular signaling pathways, and modulation of inflammatory responses. Its activity can be influenced by factors such as selenium availability, oxidative stress levels, and the presence of other antioxidants. Dysregulation of GPx1 has been associated with various diseases, including cancer and neurodegenerative disorders, highlighting its significance in health and disease. Overall, GPx1 is a key player in the body's defense against oxidative stress, contributing to overall cellular health and function.

Glutathione peroxidase 1

1451392-36-1: Glutathione peroxidase 1 (GPx1) is an important antioxidant enzyme that plays a crucial role in protecting cells from oxidative damage. It catalyzes the reduction of hydrogen peroxide and organic peroxides, utilizing glutathione as a substrate, which is a tripeptide composed of glutamate, cysteine, and glycine. GPx1 is primarily found in the cytoplasm of cells and is vital for maintaining cellular redox balance. The enzyme is characterized by its selenium-containing active site, which is essential for its catalytic activity. GPx1 is involved in various physiological processes, including detoxification of reactive oxygen species, regulation of cellular signaling pathways, and modulation of inflammatory responses. Its activity can be influenced by factors such as selenium availability, oxidative stress levels, and the presence of other antioxidants. Dysregulation of GPx1 has been associated with various diseases, including cancer and neurodegenerative disorders, highlighting its significance in health and disease. Overall, GPx1 is a key player in the body's defense against oxidative stress, contributing to overall cellular health and function.

<p>GPX1 is a monoclonal antibody that recognizes the protein GPx-1, which is involved in the protection of cells against oxidative stress. The antibody can be used as a research tool to study GPx-1 interactions with ions, proteins and receptors. It also has potential therapeutic applications.</p>

CAS 1451392-36-1

Glutathione peroxidase 1

GPX1 human

Ref: 3D-BIC39236