CAS 1451750-73-4

Pentanedioic acid, 2-hydroxy-4-methylene-, 1,5-diethyl ester

Description:

Pentanedioic acid, 2-hydroxy-4-methylene-, 1,5-diethyl ester, also known by its CAS number 1451750-73-4, is an organic compound characterized by its diester structure derived from pentanedioic acid. This compound features two ethyl ester groups attached to the carboxylic acid moieties, which contribute to its solubility and reactivity. The presence of a hydroxy group and a methylene bridge in the structure enhances its potential for various chemical reactions, including esterification and condensation. Typically, such compounds exhibit moderate to high polarity due to the presence of functional groups, which can influence their solubility in polar solvents. Additionally, the diethyl ester configuration suggests that it may have applications in organic synthesis, potentially serving as an intermediate in the production of pharmaceuticals or agrochemicals. Its physical properties, such as boiling point and melting point, would depend on the specific molecular interactions and the presence of functional groups. Overall, this compound represents a versatile building block in organic chemistry.

Formula: C₁₀H₁₆O₅

Synonyms:

• TETi76
• Pentanedioic acid, 2-hydroxy-4-methylene-, 1,5-diethyl ester

TETi76

CAS: 1451750-73-4

TETi76

Purity: ≥95%

Molecular weight: 216.23g/mol

Ref: 54-OR1001970

TETi76

CAS: 1451750-73-4

TETi76 is an orally active inhibitor from the TET family, demonstrating IC50 values of 1.5, 9.4, and 8.8 μM against TET1, TET2, and TET3, respectively. The compound competitively binds to the active sites of TET enzymes, reducing cytosine hydroxymethylation and restricting clonal growth in mutated TET2 in vitro and in vivo, without affecting the growth of normal hematopoietic progenitor cells. TETi76 is utilized in leukemia research.

Formula: C₁₀H₁₆O₅

Color and Shape: Solid

Molecular weight: 216.23

Ref: TM-T200365

TETi76

CAS: 1451750-73-4

Purity: 97%

Molecular weight: 216.1

Ref: 10-F556286