CAS 145224-92-6

Cholan-24-oic acid, 3,12-dihydroxy-, sodium salt, hydrate (1:1:1), (3α,5β,12α)-

Description:

Cholan-24-oic acid, 3,12-dihydroxy-, sodium salt, hydrate (1:1:1), commonly referred to as a sodium salt of a bile acid derivative, is characterized by its structural features that include hydroxyl groups at the 3 and 12 positions of the cholanic acid backbone. This compound is typically soluble in water due to the presence of the sodium salt form, which enhances its hydrophilicity. The hydrate form indicates that it contains water molecules in its crystalline structure, which can influence its stability and solubility. As a bile acid derivative, it may play a role in biological processes such as lipid metabolism and absorption. Its stereochemistry, denoted by the (3α,5β,12α) configuration, suggests specific spatial arrangements of its functional groups, which can affect its biological activity and interaction with receptors. Overall, this compound is of interest in biochemistry and pharmacology, particularly in studies related to cholesterol metabolism and potential therapeutic applications.

Formula: C₂₄H₄₀O₄·H₂O·Na

InChI: InChI=1S/C24H40O4.Na.H2O/c1-14(4-9-22(27)28)18-7-8-19-17-6-5-15-12-16(25)10-11-23(15,2)20(17)13-21(26)24(18,19)3;;/h14-21,25-26H,4-13H2,1-3H3,(H,27,28);;1H2/t14-,15-,16-,17+,18-,19+,20+,21+,23+,24-;;/m1../s1

InChI key: InChIKey=HKLBTQUQYACMJN-WTCAICSISA-N

SMILES: C[C@@]12[C@]([C@]3([C@@]([C@]4(C)[C@](CC3)(C[C@H](O)CC4)[H])(C[C@@H]1O)[H])[H])(CC[C@@]2([C@@H](CCC(O)=O)C)[H])[H].[Na].O

Synonyms:

• Cholan-24-oic acid, 3,12-dihydroxy-, monosodium salt, monohydrate, (3α,5β,12α)-
• Cholan-24-oic acid, 3,12-dihydroxy-, sodium salt, hydrate (1:1:1), (3α,5β,12α)-
• Sodium (3Α,5Β,12Α)-3,12-Dihydroxycholan-24-Oate Hydrate
• Sodium (8Xi,9Xi,14Xi)-3,7,12-Trioxocholan-24-Oate
• Sodium deoxycholate monohydrate

Sodium deoxycholate monohydrate, 98%

CAS: 145224-92-6

Sodium deoxycholate monohydrate is used as a solubilization agent for estrogen synthetase from human placental microsomes. It is also used to study the immobilization of lipoxygenase in an alginate-silicate gel matrix and to investigate the in vitro dissolution of gall stones. This Thermo Scientifi

Formula: C₂₄H₄₁NaO₅

Purity: 98%

Color and Shape: White, Powder

Molecular weight: 432.58

Ref: 02-B20759

Cholan-24-oic acid, 3,12-dihydroxy-, sodium salt, hydrate (1:1:1), (3α,5β,12α)-

CAS: 145224-92-6

Formula: C₂₄H₄₁NaO₅

Purity: 99%

Color and Shape: Solid

Molecular weight: 432.5691

Ref: IN-DA001KP5

Sodium Deoxycholate Monohydrate

CAS: 145224-92-6

Sodium Deoxycholate Monohydrate

Purity: 99%

Molecular weight: 432.57g/mol

Ref: 54-OR1025136

Sodium deoxycholate monohydrate

Controlled Product

CAS: 145224-92-6

Deoxycholic acid is a bile acid that plays an important role in the digestion of fat. Sodium deoxycholate is used as a detergent to solubilize biological samples and increase their sensitivity to analysis. Deoxycholic acid has been shown to bind to toll-like receptor 4 (TLR4) and induce a response in cells that can be measured using fluorescence probes. It also has shown activity against infectious diseases, such as primary sclerosing cholangitis, by inducing apoptosis. Sodium deoxycholate monohydrate is used as an injection solution for bowel disease.

Formula: C₂₄H₃₉O₄Na·H₂O

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 432.57 g/mol

Ref: 3D-FD47400

Deoxycholic Acid Sodium Salt Monohydrate (Sodium Deoxycholate Monohydrate) Bacto grade, 99%

CAS: 145224-92-6

Formula: C₂₄H₃₉NaO₄·H₂O

Purity: min. 99%

Color and Shape: White to off-white, Crystalline powder, Clear, Colourless to light yellow

Molecular weight: 432.59

Ref: SR-96876

Sodium deoxycholate monohydrate, 97%

CAS: 145224-92-6

Sodium deoxycholate, 302-95-4, is a bile acid salt that contains a deoxycholate group and is commonly used as a choleretic and an anionic detergent. Learn more.

Formula: C₂₄H₄₁NaO₅

Purity: 97%

Color and Shape: White to pale cream, Powder

Molecular weight: 432.58

Ref: 02-J62288